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Recruiting NCT06269939

Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI

No phase Interventional Aging

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: STEM.
Who it may be relevant to
Registry conditions: Aging. Basic parameters: from 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and Mild Cognitive Impairment

Overview

The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in an aging population.

Detailed description

Memory enhancing techniques have been incorporated into an 8-session treatment protocol, Strategy Based Training to Enhance Memory (STEM), designed to teach participants about each of the techniques, train them on how to apply the techniques in daily life and practice their application to daily life memory demanding situations. The protocol includes teaching participants over age 60 how to restructure a memory demanding situation in order to make optimal use of the techniques.

Interventions

  • Behavioral STEM
    Memory technique training

Primary outcome measures

  • Verbal Leaning task [Time frame: Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]]
  • Participation in Everyday life [Time frame: Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]]
Secondary outcome measures (1)
  • Functional Neuroimaging [Time frame: Two points in time: pre-treatment, immediately following treatment]

Eligibility criteria

Inclusion criteria

  • Inclusion Criteria:
  • read and speak English fluently

Exclusion criteria

  • prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke).
  • history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis).
  • significant alcohol or drug abuse history (inpatient treatment).
  • Benzodiazepines and steroid use
  • Diagnosis of dementia

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • Kessler Foundation — East Hanover

Identifiers

NCT: NCT06269939 · R-1253-24

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗