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Recruiting NCT06262464

An OCD Prevention Programme for at Risk Adults

No phase Interventional Obsessive-Compulsive Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Prevention.
Who it may be relevant to
Registry conditions: Obsessive-Compulsive Disorder. Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Romania
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Efficacy of an OCD Prevention Programme for at Risk Adults: a Randomized Clinical Trial

Overview

The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.

Detailed description

After being informed about the study and giving written informed consent, all eligible participants will be randomised into the experimental group or the control group (TAU). Participants will be blind to the group allocation.

The experimental group will undergo a two weeks OCD prevention program, consisting of three group sessions per week.

The control group will not receive any intervention.

Researchers will compare the experimental group to the control group to test wether the prevention programme is efficient in reducing OCD symptomatology.

Interventions

  • Behavioral Prevention
    A cognitive-behavioural prevention programme.

Primary outcome measures

  • Change from baseline in OCD symptoms on the OCI-R after the intervention [Time frame: Baseline and Week 2]
  • Change from baseline in depressive symptoms on the PHQ-9 after the intervention [Time frame: Baseline and Week 2]
  • Change from baseline in anxiety symptoms on the GAD-7 after the intervention [Time frame: Baseline and Week 2]
Secondary outcome measures (4)
  • Change from baseline in experiential avoidance on the EAQ after the intervention [Time frame: Baseline and Week 2]
  • Change from baseline in cognitive distortions on the OBQ-44 after the intervention [Time frame: Baseline and Week 2]
  • Change from baseline in uncertainty intolerance on the IUS after the intervention [Time frame: Baseline and Week 2]
  • Change from baseline in resilience on the RSA after the intervention [Time frame: Baseline and Week 2]

Eligibility criteria

Inclusion criteria

\- age over 18

Exclusion criteria

  • clinically diagnosed OCD
  • current psychiatric/psychotherapeutic treatment
  • personality disorder diagnosis
  • suicidal ideation

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Prevention

Study locations

Romania · 1 center
  • Babes-Bolyai University, Faculty of Psychology and Educational Sciences, Department of Cli — Cluj-Napoca

Publications

  • Cardos RAI, Dumitru EP, David OA. OCD: protocol for the development and evaluation of a cognitive-behavioral prevention program for obsessive-compulsive disorder. BMC Psychiatry. 2024 May 9;24(1):348. doi: 10.1186/s12888-024-05791-3. PMID 38724961

Identifiers

NCT: NCT06262464 · 17.361/ 07.12.2023

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗