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Not yet recruiting NCT06260046

Effect of Sufentanil on the Postoperative Pain

No phase Interventional Postoperative Pain, Acute

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Sufentanil, Remifentanil.
Who it may be relevant to
Registry conditions: Postoperative Pain, Acute. Basic parameters: from 19 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Analgesic Effect of Intraoperative Sufentanil on Postoperative Pain in Patients Undergoing Robot-assisted Nephrectomy: a Prospective Randomized Controlled Trial

Overview

This study is a randomized, controlled trial. A total of 48 patients will be randomized to receive sufentanil or remifentanil during robot-assisted nephrectomy surgery.

Interventions

  • Drug Sufentanil
    Induction: sufentanil TCI 0.3 ng/ml Maintenance: sufentanil TCI 0.05-0.5 ng/ml
  • Drug Remifentanil
    Induction: remifentanil TCI 3 ng/ml Maintenance: remifentanil TCI 0.5-5 ng/ml

Primary outcome measures

  • opioid consumption [Time frame: During post-anesthesia care unit(PACU) stay, until 1 hour]
Secondary outcome measures (4)
  • Richmond Agitation-Sedation scale [Time frame: During post-anesthesia care unit(PACU) stay, until 1 hour]
  • Incidence of postoperative nausea and vomiting [Time frame: During post-anesthesia care unit(PACU) stay, until 1 hour]
  • Number of patients who administered antiemetics [Time frame: During post-anesthesia care unit(PACU) stay, until 1 hour]
  • Pain score [Time frame: immediately after surgery, 15minutes, 30minutes, 60minutes after surgery]

Eligibility criteria

Inclusion criteria

  • Patients who undergo elective robot-assisted nephrectomy surgery
  • American Society of Anesthesiologists grade 1,2,3
  • Age > 18 years old

Exclusion criteria

  • Refuse to participate to the study
  • Allergic history of opioid
  • chronic pain
  • opioid user before surgery
  • MAO inhibitor user
  • Severe respiratory insufficiency

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Prevention

Study locations

South Korea · 1 center
  • Seoul National University Bundang Hospital — Seongnam

Identifiers

NCT: NCT06260046 · Robot Nx-SFTN

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗