This Research Project Studies the Relationship Between OSA and Nocturia.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Voiding diary.
- Who it may be relevant to
- Registry conditions: Obstructive Sleep Apnea. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Czechia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Academic Research Project Studies the Relationship Between Obstructive Sleep Apnoea and the Occurrence of Nocturia.
Overview
The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.
Detailed description
The observation study will be performed on patients diagnosed with obstructive sleep apnoea. Patients will undergo routine examination for sleep apnoea and will be asked to fill in voiding diaries for 48 hours. The main goal of the study is to find whether there are any parameters of sleep apnoea associated with occurrence of the nocturia.
Interventions
- Other Voiding diary
The patients with diagnosed OSA will be asked to fill in the voiding diary.
Primary outcome measures
- Change in the parameters of sleep apnoea - (apnea-hypopnea index - AHI) [Time frame: 3 months]
- Change in the parameters of sleep apnoea - oxygen desaturation index (ODI) [Time frame: 3 months]
- Change in the parameters of sleep apnoea - time under 90% saturation (T90) [Time frame: 3 months]
Secondary outcome measures (3)
- Change in the data from the voiding diary - functional capacity of the bladder [Time frame: 3 months]
- Change in the data from the voiding diary - daily diuresis [Time frame: 3 months]
- Change in the data from the voiding diary - number of voiding episodes [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- patients diagnosed obstructive sleep apnoea (OSA )
- Apnea-Hypopnea Index (AHI) > 15
- ability to fill in the voiding diaries
- signed informed consent
Exclusion criteria
- patients using diuretics
- patients with malignancies
- pregnancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Czechia · 1 center
- University Hospital Ostrava — Ostrava
Publications
- Berry RB, Brooks R, Gamaldo C, Harding SM, Lloyd RM, Quan SF, Troester MT, Vaughn BV. AASM Scoring Manual Updates for 2017 (Version 2.4). J Clin Sleep Med. 2017 May 15;13(5):665-666. doi: 10.5664/jcsm.6576. No abstract available. PMID 28416048
- Lowenstein L, Kenton K, Brubaker L, Pillar G, Undevia N, Mueller ER, FitzGerald MP. The relationship between obstructive sleep apnea, nocturia, and daytime overactive bladder syndrome in women. Am J Obstet Gynecol. 2008 May;198(5):598.e1-5. doi: 10.1016/j.ajog.2008.02.024. PMID 18455544
- Oztura I, Kaynak D, Kaynak HC. Nocturia in sleep-disordered breathing. Sleep Med. 2006 Jun;7(4):362-7. doi: 10.1016/j.sleep.2005.10.004. Epub 2006 Mar 24. PMID 16564213
- Umlauf MG, Chasens ER, Greevy RA, Arnold J, Burgio KL, Pillion DJ. Obstructive sleep apnea, nocturia and polyuria in older adults. Sleep. 2004 Feb 1;27(1):139-44. doi: 10.1093/sleep/27.1.139. PMID 14998251
- Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993 Apr 29;328(17):1230-5. doi: 10.1056/NEJM199304293281704. PMID 8464434
Identifiers
NCT: NCT06239883 · 468/2021