HUTT to Assess Cardiac Autonomic Nervous Function
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Autonomic Nervous System Diseases. Basic parameters: 12 years — 85 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Composite Autonomic Scoring Scale and HUTT to Assess Cardiac Autonomic Nervous Function: A Preliminary Study
Overview
Autonomic nervous system diseases can cause abnormalities in the circulatory system, leading to malignant arrhythmia and sudden cardiac death. Standardized, operable, and simplified diagnostic indicators are urgently needed to evaluate autonomic nervous function, particularly cardiac autonomic nervous function. The investigators use HUTT in order to provide data support for cardiac autonomic nervous system evaluation.
Detailed description
In this study, 169 samples with vertical tilt test and 24-h Holter ECG data from February 13, 2023 to October 31, 2023 were selected. The AC, DC, and 24-h HRV were compared with the CASS to identify the indicators with the strongest correlation with the CASS sympathetic and vagus nerve scores. The best index was selected, and the score intervals were delimited. The sensitivity and specificity of the defined vagal and sympathetic intervals were analyzed.
Primary outcome measures
- To find the indicators which are most correlated to the sympathetic and vagus nerves. [Time frame: February 13, 2023 to December 31, 2025]
Eligibility criteria
Inclusion criteria
- Vertical tilt test and 24-hour holter electrocardiogram were performed at the same time
- Receive treatment in our hospital.
Exclusion criteria
- Taking benzodiazepines or hypotensive drugs within 24 hours
- Combined with mental illness, severe dementia, serious organ disease
- Severe arrhythmia, deep breathing and poor coordination of Valsaval movements affected the interpretation of results.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- The First Hospital Of Hebei Medical University — Shijiazhuang
Identifiers
NCT: NCT06236945 · 20230213