Immune and Cognitive Benefits of Mango Intake in Young Adults
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Mango group.
- Who it may be relevant to
- Registry conditions: Cognition, Immunity. Basic parameters: 18 years — 30 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Immune and Cognitive Benefits of Mango Intake in Young Adults: A Randomized Trial
Overview
The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years
Detailed description
The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30. To accomplish these objectives, a randomized controlled, parallel design study is proposed with two groups consuming their habitual diet, but with one (Mango group) receiving 1.5 servings of mango/day and the other (Control group) abstaining from eating any mango for the duration of the study.
Interventions
- Dietary supplement Mango group
Participants will consume 1.5 cups of mangos per day for 12 weeks.
Primary outcome measures
- Changes in lymphocyte populations [Time frame: baseline to 12 weeks]
- Changes in Lymphocyte activity [Time frame: baseline to 12 weeks]
- Changes in cytokine production [Time frame: baseline to 12 weeks]
- Changes in serum inflammatory cytokine concentration [Time frame: baseline to 12 weeks]
- changes from baseline in global cognitive composite score [Time frame: baseline to 12 weeks]
- Change in serum brain-derived neurotrophic factor (pg/mL) [Time frame: baseline to 12 weeks]
Eligibility criteria
Inclusion criteria
- Male and female college students aged 18-30 years
Exclusion criteria
- known intolerance or allergy to mangos
- regular intake of mangos and/or fruits of a similar nutritional content such as peach, nectarine, papaya, apricot and cantaloupe
- using cognition and/or immune-boosting supplements or vitamins
- recent exposure to antibiotics and corticoids
- uncontrolled chronic diseases and mental illnesses, clinical depression, and immunocompromised state
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
United States · 1 center
- Loma Linda University School of Public Health — Loma Linda
Identifiers
NCT: NCT06229262 · 5230334