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Recruiting NCT06226077

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

Phase I / Phase II Interventional Obesity Insufficient Sleep

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: sleep extension intervention, contact control intervention.
Who it may be relevant to
Registry conditions: Obesity, Insufficient Sleep. Basic parameters: 21 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behaviors among African Americans (AAs), given the high disease burdens associated with low physical activity, insufficient sleep, and obesity. There will be two phases to the proposed research. Phase 1 (Aim 1) will encompass formative research and community engagement activities, and Phase 2 (Aim 2a and 2b) will be a randomized clinical trial. The primary goal of Aim 1 is to conduct in-depth qualitative interviews in order to: (1) better understand sleep-related social contextual factors, knowledge, behaviors, and beliefs, and (2) discuss and receive feedback on an existing sleep intervention design and materials. The primary goal of Aim 2 is to explore the feasibility, satisfaction, and preliminary efficacy of a sleep intervention to increase sleep and physical activity (PA) among sedentary and short sleeping (≤6 hrs/night) African American adults with overweight/obesity, compared to a contact control group. (Aim 2a) An additional exploratory (Aim 2b) examines changes in cancer-relevant biomarkers between those who received the intervention vs the control condition (n = 20). Data will be collected from a sample of 20 participants (10 per condition) who volunteer to have their blood drawn pre- and post-intervention. There are two phases of the study, and information gained during Phase 1 (Aim 1) will be used to inform Phase 2 (Aim 2). Thus, additional modifications to the protocol will be submitted prior to engagement in Phase 2.

Interventions

  • Behavioral sleep extension intervention
    The sleep intervention aims to increase sleep duration by one-hour (15 minutes/week) over the course of 4-weeks using components from Cognitive Behavioral Therapy for Insomnia. More specifically, the intervention consists of psychoeducation, sleep extension, sleep hygiene, and stimulus control. Participants will meet with Dr. Wu or a trained staff member once a week over the course of 4-weeks via Zoom. The intervention will be adapted based on feedback from the community, knowledge gained during
  • Behavioral contact control intervention
    The control condition is a contact-control intervention whereby participants will meet with Dr. Wu or a trained staff member once-week over the course of 4-weeks to receive education materials from the Healthy Homes intervention developed by the UT School of Public Health.

Primary outcome measures

  • Feasibility of the sleep intervention [Time frame: 10 weeks]
  • Satisfaction with the sleep intervention [Time frame: 10 weeks]

Eligibility criteria

Inclusion criteria

Phase 1:

  • Not meeting Physical Activity Guidelines
  • age range: 21 to 75 years
  • body mass index: ≥25.0 kg/m2
  • average self-reported habitual sleep duration of ≤6 hours
  • self-identify as Black or African American

Phase 2:

  • Not meeting Physical Activity Guidelines
  • age range: 21 to 75 years
  • body mass index: ≥25.0 kg/m2
  • average self-reported habitual sleep duration of ≤6 hours
  • self-identify as Black or African American

Exclusion criteria

Phase 1:

  • Self-reported organ-related disorder (COPD, cardiac arrhythmia, gastro-esophageal disorder)
  • pregnant or less than 4 months postpartum
  • infant living in household less than 1 year old

Phase 2:

  • Self-reported organ-related disorder (COPD, cardiac arrhythmia, gastro-esophageal disorder)
  • pregnant or less than 4 months postpartum
  • infant living in household less than 1 year old

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

United States · 1 center
  • University of Minnesota — Minneapolis

Identifiers

NCT: NCT06226077 · 2022LS170 (B)

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗