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Enrolling by invitation NCT06225388

Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.

No phase Interventional Muscle Soreness Perceived Recovery Perceived Exertion Affective Response

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Compression socks, Placebo socks.
Who it may be relevant to
Registry conditions: Muscle Soreness, Perceived Recovery, Perceived Exertion, Affective Response. Basic parameters: 18 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Brazil
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effect of Wearing a Compression Sock During Running on Delayed Onset Muscle Soreness in Distance Runners: A Randomised, Double-blind, Sham-controlled, Crossover Trial.

Overview

Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness. There is still a paucity of interventions that can effectively minimise these symptoms in distance runners.

Detailed description

Our primary aim is to explore the effect of compression socks during running on delayed onset muscle soreness after running. Our secondary aims are to explore the effects of compression socks during running on perceived recovery, perceived exertion, affective response, and heart rate after running. This is a randomised, double-blind, sham-controlled crossover trial. Forty-four participants will be recruited via social media, running clubs and the running coaches' network of the research team. Participants will be randomised to complete a running protocol under two conditions (compression socks or sham socks). After that, there will be a wash-out period of 7 to 10 days, and participants will repeat the running protocol under the other conditions. Primary outcome: lower limb muscle soreness will be collected, using a 0-100 numerical pain scale, immediately, 24 hours and 48 hours after the running protocol, with 24 hours post-protocol being the primary timepoint. Secondary outcomes: perceived recovery will be collected, using a 0-10 scale immediately, 24 hours and 48 hours after the running protocol. Perceived exertion, affective response, and heart rate will be registered only immediately after the protocol. Between-group differences will be explored using linear mixed models.

Interventions

  • Other Compression socks
    A pair of socks corresponding to the intervention allocated will be given to the participant, by an investigator who will not participate in the evaluation, in a dark plastic bag to avoid any visual influence. We will adopt strategies to prevent information about the socks from influencing the participants' behaviour: (1) the compression and placebo socks will have the same colour, any visual detail and branding will be covered. Words or logos from the compression sock will be covered, so partic
  • Other Placebo socks
    The compression and placebo socks will have the same colour, any visual detail and branding will be covered. Words or logos from the compression sock will be covered, so participants are unable to differentiate them. (2) After performing the running protocol, participants will remove their socks and return them to the investigator.

Primary outcome measures

  • Lower limb muscle soreness. [Time frame: 24 hours post-intervention.]
Secondary outcome measures (5)
  • Lower limb muscle soreness. [Time frame: 5 minutes post-intervention, and 48 hours post-intervention.]
  • Perceived recovery. [Time frame: 5 minutes post-intervention, 24 hours, and 48 hours post-intervention.]
  • Perceived exertion [Time frame: 5 minutes post-intervention.]
  • Affective response [Time frame: 5 minutes post-intervention.]
  • Heart rate [Time frame: Through the intervention, an average of 30 minutes.]

Eligibility criteria

Inclusion criteria

  • Run consistently in the last six months (at least three times a week and at least 10 kilometres per week);
  • Runners who did not run further than 42 kilometres in the last month.

Exclusion criteria

  • Pregnancy;
  • Any lower limbs fracture in the last 12 months;
  • History of lower limb arthroplasty or osteotomy, previous venous thrombosis, kidney disease;
  • Any running-related injury in the last six months. A running-related injury will be considered the presence of lower limb pain that caused restriction, stoppage of running (distance, speed, duration, or training) for at least seven days or three consecutive scheduled training sessions or the need for a health professional treatment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

Brazil · 1 center
  • Centro Universitário Augusto Motta — Rio de Janeiro

Identifiers

NCT: NCT06225388 · 01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗