Biomarkers in Prediction of AMI
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sequential blood samples.
- Who it may be relevant to
- Registry conditions: Acute Mesenteric Ischemia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Estonia, Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Biomarkers In Prediction of Acute Mesenteric Ischaemia: a Prospective Multicentre Study (BIPAMI Study)
Overview
Current study will be undertaken to identify combinations of biomarkers that can reliably identify acute mesenteric ischaemia (AMI) and distinguish between non-transmural and transmural ischaemia. Different combinations of biomarkers for different sub-types and severity of AMI, and different time points of measurement after onset of symptoms.
Interventions
- Diagnostic test Sequential blood samples
Sequential blood samples for diagnostic tests is the only intervention in thei study
Primary outcome measures
- Rate of correctly predicted cases of acute mesenteric ischaemia [Time frame: 10 months]
Eligibility criteria
Inclusion criteria
- Age 18 years or older
- Initial decision in favour of further diagnostics of mesenteric ischaemia
Exclusion criteria
- Age <18 years
- Consent declined by patient or next of kin (delayed consent)
- Chronic mesenteric ischaemia without an acute event
- Immediate decision for withdrawal of further diagnostics and active treatment
- Referral from another hospital with already established diagnosis of AMI
- AMI diagnosed at surgery without previously having been considered
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
Estonia · 1 center
- Tartu University Hospital — Tartu
Switzerland · 1 center
- Lucerne Cantonal Hospital — Lucerne
Publications
- Tamme K, Acosta S, Biloslavo A, Bjorck M, Casian D, Damaskos D, Forbes A, Kase K, Kisand K, Lakbar I, Mihnovits V, Murruste M, Mandul M, Nuzzo A, Padar M, Starkopf J, Visconti D, Reintam Blaser A. Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol. BMC Surg. 2024 Jul 3;24(1):201. doi: 10.1186/s12893-024-02491-3. PMID 38961419
Identifiers
NCT: NCT06212921 · BIPAMI study