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KeyScope Study in Uganda

No phase Interventional Abdominal Neoplasm

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: KeySuite.
Who it may be relevant to
Registry conditions: Abdominal Neoplasm. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Uganda
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

KeyScope: First-In-Human Clinical Study for Cancer Diagnosis in Uganda

Overview

KeyScope and KeyLoop (collectively called KeySuite) are laparoscopic prototypes that the investigators have designed for the resources, needs and challenges of low- and middle- income countries (LMICs). KeyScope is a laparoscope that plugs into a laptop computer to display images during surgery. It links to a telementoring application so that experienced surgeons can mentor surgeons in capacity-building partnerships. KeyLoop is a laparoscopic retractor that lifts the abdominal wall during surgery, obviating the need for a constant power supply and medical-grade carbon dioxide. The investigators will perform a clinical First-in-Human study at the Uganda Cancer Institute. Ugandan surgeons will use the KeySuite devices to perform biopsies of intra-abdominal tumors.

Interventions

  • Device KeySuite
    KeyScope and KeyLoop will be used to perform biopsies of intra-abdominal masses and cancers.

Primary outcome measures

  • Establish the clinical safety KeySuite [Time frame: Day of surgery]
Secondary outcome measures (3)
  • Time to complete surgery [Time frame: Day of surgery]
  • Estimated blood loss [Time frame: Day of surgery]
  • Surgical injuries and adverse events [Time frame: Day of surgery]

Eligibility criteria

Inclusion criteria

  • diagnosis of intra-abdominal mass suspicious for cancer
  • body mass index (BMI) of 18-30
  • weight 20-100kg
  • biopsy necessary to determine cancer diagnosis and classify pathology
  • surgeon determine that laproscopic biopsy it technically appropriate

Exclusion criteria

  • significant comorbidities
  • previous major abdominal surgery
  • current pregnancy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

Uganda · 1 center
  • Uganda Cancer Institute — Kampala

Identifiers

NCT: NCT06212570 · Pro00110170

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗