Drugs Experience for Adolescents With Anorexia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Semi-structured interviews with visual mediations, Semi-structured interviews.
- Who it may be relevant to
- Registry conditions: Anorexia Nervosa, Psychotropic Drugs, Adolescent. Basic parameters: from 12 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Subjective Experience of Psychotropic Drugs Among Adolescents (Their Parents and Professionals) With Anorexia Nervosa
Overview
The purpose of this study is to access to the experiences of adolescents, their parents and healthcare professionals regarding psychotropic drugs in anorexia nervosa. No preconceived ideas (according to qualitative methods) but a question: what are the participants' perceptions and experiences of psychotropic drugs in anorexia nervosa? In an adolescent medicine department.
Detailed description
Psychotropic prescription is common to adolescents suffering from anorexia nervosa. A first qualitative study (E3A Protocol "Experience of adolescents with anorexia nervosa toward antidepressants") looked at the experience of antidepressants among 15 adolescents suffering from anorexia nervosa. Analysis of the interviews identified two meta-themes:
1. Reactions to the proposal of antidepressant with an opposition phase (about the existence of depressive symptoms and about negative preconceptions) and need to share with family and other teenagers. 2. Reactions to antidepressant use with ambivalence and an initial perception of coercion, and effects of antidepressants (psychological effects, effects on the body and on anorexia nervosa and effects perceived through the eyes of others).
Nine adolescents (out of 15) were also taking an atypical antipsychotic (APA) often prescribed in case of anorexia nervosa resistance.
The need to share with family about the proposal of antidepressant and the effects perceived through the eyes of others (including parent's eyes) lead us to take an interest in parents perceptions.
Two decisive periods were identified: What do healthcare professionals think about psychotropic treatments for anorexia nervosa in adolescence? How do they propose treatment?
Interviewing teenagers, their parents as well as healthcare professionals, will enable to access to the complexity of representations and experiences of these psychotropic drugs in anorexia nervosa.
Interventions
- Other Semi-structured interviews with visual mediations
Semi-structured interviews with visual mediations / An hour-long interview - Other Semi-structured interviews
Semi-structured interviews
Primary outcome measures
- Semi-structured interview [Time frame: Day of inclusion]
Secondary outcome measures (2)
- Semi-structured interview [Time frame: Day of inclusion]
- Semi-structured interview [Time frame: Day of inclusion]
Eligibility criteria
Inclusion criteria
Adolescents :
- Aged 12 to 25 years
- Suffering from anorexia nervosa (restrictive or mixed) according to DSM-5 (Diagnostic and Statistical Manual) criteria
- Received psychotropic drugs (antidepressant treatment and/or APA) during their care, either ongoing or discontinued before this study started
Parents of adolescents suffering from anorexia nervosa for whom a psychotropic drug has been prescribed and whose adolescents meet inclusion criteria
Healthcare Professionals working with adolescents suffering from eating disorders
Exclusion criteria
Adolescents :
- Atypical eating disorder that does not meet the DSM-5 criteria for restrictive or mixed anorexia nervosa
- BMI<15
- Prescription of an antidepressant other than an SSRI (Selective Serotonin Reuptake Inhibitor)
- Prescription of an APA for the indication of psychotic symptoms
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
France · 1 center
- Maison de Solenn Maison des Adolescents, Cochin Hospital — Paris
Publications
- Ludot-Gregoire M, David V, Carretier E, Lachal J, Moro MR, Blanchet C. Subjective Experience of Antidepressant Prescription Among Adolescents With Anorexia Nervosa. Front Psychiatry. 2022 Apr 4;13:770903. doi: 10.3389/fpsyt.2022.770903. eCollection 2022. PMID 35444576
Identifiers
NCT: NCT06211517 · APHP230062 · 2022-A02141-42