Early Warning and Classification Model for Acute Non-traumatic Chest Pain
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization.
- Who it may be relevant to
- Registry conditions: Chest Pain. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
A Prospective Study of Acute Nontraumatic Chest Pain - Warning and Classification
Overview
Acute non-traumatic chest pain is one of the common causes of presentation in emergency patients, but the causes of acute non-traumatic chest pain are complex, the severity of the condition varies greatly, and the specificity of symptoms is not high. Machine learning and intelligent auxiliary models can greatly shorten the time of clinical decision-making, and improve the accuracy of etiological diagnosis in patients with chest pain, reduce the rate of misdiagnosis and missed diagnosis, and provide a clear direction for further treatment.
Detailed description
Prospective observational studies used outpatient and follow-up information to construct an auxiliary early warning model of acute non-traumatic chest pain based on federated learning, and optimized the accuracy of early warning models through retrospective and prospective studies of large cohort data, and established an efficient and stable early warning and classification model for acute non-traumatic chest pain.
Interventions
- Combination product Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization
Examination： Electrocardiogram、 imaging examination、 X-ray, CTA, bedside echocardiography. Laboratory test results of patients, including complete blood count, D-dimer, myocardial injury markers, sST2, MPO, and other indicators. History of cardiovascular and pulmonary vascular drug therapy: Antithrombotic therapy (type, measurement) , Anticoagulation therapy (type, metering), Other drug treatments (type, measurement)
Primary outcome measures
- Adverse events [Time frame: 30 days after presenting to the emergency departments(ED)]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years
- Symptom onset or worsening within 24 hours before presentation, with a chief complaint of acute chest pain meeting the broad definition of chest pain (2021 AHA)
- Presentation to the emergency department, with a clinical diagnosis consistent with non-traumatic chest pain
- Signed informed consent
Exclusion criteria
- traumatic chest pain
- systemic pain caused by malignant tumors or rheumatic diseases involving the chest
- Patients were lost to follow-up
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Xiaonan He — Beijing
Identifiers
NCT: NCT06196307 · F0213-62272327