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Recruiting NCT06192771

Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically

No phase Interventional Dysphagia Head and Neck Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: ESSI-SURG, Standard-of-Care.
Who it may be relevant to
Registry conditions: Dysphagia, Head and Neck Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Oral cavity cancer (OCC) is one of the most common cancers worldwide, with tongue cancer being one of the most common subtypes. Patients with oral cancers can experience painful swallowing, swallowing difficulty (dysphagia), and associated weight loss long after surgery. Not only is dysphagia an independent predictor of quality of life (QoL) in cancer survivorship, it can also have a devastating impact on the health of patients resulting from complications such as pneumonia, malnutrition and feeding tube dependence. Emerging evidence suggests that patients undergoing surgery benefit from engaging with speech-language pathologists (SLPs) before problems arise, to learn swallow strategies that may become useful in their rehabilitation. This in turn has the potential to reduce complications and minimize the length of feeding tube dependency. This study will assess the feasibility of conducting a prospective clinical trial that would evaluate the effects on patient health, function and overall benefit of early and systematic SLP speech and swallowing intervention for head and neck cancer patients planned for curative surgical treatment. We will also assess long-term changes in select clinical and patient-reported outcomes comparing their status before, and one month after, treatment.

Interventions

  • Behavioral ESSI-SURG
    Patients will receive 3 face-to-face sessions with a speech-language pathologist (SLP), each with a specific goal, namely: pre-surgical educational, a post-operative day 3 therapy, and post-operative day 7 therapy. Following discharge from hospital, participants will be seen by an SLP for 4 weekly sessions, offered via telehealth or face-to-face depending on the patient's clinic schedule and/or availability.
  • Behavioral Standard-of-Care
    Participants will receive the current standard of care, which includes a referral to SLP in response to suspicion of a swallowing problem from either assessment by the medical team and/or patient report.

Primary outcome measures

  • Study feasibility as measured by rate of accrual [Time frame: Baseline to Post-Discharge Week 5]
  • Study feasibility as measured by attrition [Time frame: Baseline to Post-Discharge Week 5]
  • Study feasibility as measured by data fidelity for clinician assessments [Time frame: Baseline to Post-Discharge Week 5]
  • Study feasibility as measured by data fidelity for patient-reported outcomes [Time frame: Baseline to Post-Discharge Week 5]

Eligibility criteria

Inclusion criteria

  • Newly diagnosed patients with at least T2 stage tongue SCC who are planned for partial glossectomy and free flap reconstruction and are anticipated to achieve a post-operative independent oral intake.
  • Proficient in spoken and written English

Exclusion criteria

  • Patients who are planned for total glossectomy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

Canada · 1 center
  • University Health Network — Toronto

Identifiers

NCT: NCT06192771 · 23-5503

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗