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Not yet recruiting NCT06183450

Hearing and Cognition in Aging Adults

Observational Presbycusis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: auditory level, cognitive level, quality of life level.
Who it may be relevant to
Registry conditions: Presbycusis. Basic parameters: 45 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

This cohort study is expected to provide valuable insights into the complex interplay between auditory and cognitive functions and how they change over time. The results of this study will have important implications for the prevention, diagnosis, and treatment of age-related hearing and cognitive disorders

Detailed description

The aim of the study is to identify the early perceptual and cognitive alterations related to age-related hearing loss or presbycusis, establish a correlation between the degree of hearing loss and the deterioration of cognitive functions, and examine the effectiveness of hearing loss management in reversing observed cognitive impairments. This project has the potential to shed light on the importance of early detection of hearing impairments in preventing cognitive decline. The data collected from this cohort, rigorously assessed for both auditory and cognitive functions, could serve as the basis for several high-level scientific investigations.

Interventions

  • Diagnostic test auditory level
    * Evaluation of auditory thresholds through audiometric tests. * Evaluation of speech comprehension in noise through a vocal audiometry test in noise (FraMatrix). * Evaluation of spatial auditory behavior and spatial precision using a spatial discrimination test (Minimum Audible Angle) and a static sound localization test in virtual reality.
  • Diagnostic test cognitive level
    * Evaluation of attention and short-term memory functions with verbal and non-verbal tasks: Digit Span Test and Reading Span Test. * Evaluation of inhibition capacities using the Stroop Test. * Evaluation of executive functions, visual attention, reasoning, and mental arithmetic using the Raven's Matrix test.
  • Diagnostic test quality of life level
    \- Evaluation of quality of live level via Speech, Spatial and Qualities of Hearing Scale (SSQ-12) and EuroQol-5D questionnaires.

Primary outcome measures

  • Pure-ton audiometry [Time frame: 5 years]

Eligibility criteria

Inclusion criteria

  • Normal hearing (Pure Tone Audiometry < or = 20 dB)
  • Residency in one of the three neighborhoods :
  • Affiliation with a social security system

Exclusion criteria

  • Individuals under guardianship, trusteeship or curators
  • History of neurological pathologies
  • Taking of psychotropic medication.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

France · 1 center
  • Ecole d'audioprothèse — Cahors

Identifiers

NCT: NCT06183450 · RC31/22/0252 · 2023-A01415-40

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗