Radiomics of Intra-abdominal and Subcutaneous Adipose Tissue Predict the Efficacy of Bariatric Surgery (RISABS)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Obesity, Type 2 Diabetes Mellitus, Bariatric Surgery. Basic parameters: 16 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Using radiomics of intra-abdominal and subcutaneous adipose tissue and clinical features to predict the weight loss efficacy and remission of type 2 diabetes mellitus after bariatric surgery.
Detailed description
In this study, the investigator intend to collect abdominal CT from patients who are proposed to undergo bariatric surgery, to extract the radiomics of intra-abdominal fat and subcutaneous fat, and to establish a prediction model for predicting the efficacy of weight loss and remission of type 2 diabetes mellitus at 1 year, 3 years, and 5 years postoperatively, in conjunction with the clinical data.
Primary outcome measures
- Area under curve (AUC) of the weight loss prediction model after 1 year [Time frame: 1 year]
- Area under curve (AUC) of the T2DM remission prediction model after 1 year [Time frame: 1 year]
Secondary outcome measures (6)
- Area under curve (AUC) of the weight loss prediction model after 3 years [Time frame: 3 years]
- Area under curve (AUC) of the T2DM remission prediction model after 3 years [Time frame: 3 years]
- Area under curve (AUC) of the weight loss prediction model after 5 years [Time frame: 5 years]
- Area under curve (AUC) of the T2DM remission prediction model after 5 years [Time frame: 5 years]
- Area under curve (AUC) of the weight regain model [Time frame: 5 years]
- Area under curve (AUC) of the T2DM relapse model [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- BMI>27.5kg/m2; Type 2 diabetes mellitus; Patients who will undergo bariatric surgery
Exclusion criteria
- Patients without abdominal CT scan; Patients did not undergo sleeve gastrectomy or Roux-en-Y gastric bypass.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Yuntao Nie — Beijing
Identifiers
NCT: NCT06169033 · CJBariatric002