Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: titated PEEP to best static compliance.
- Who it may be relevant to
- Registry conditions: Mechanical Ventilation Pressure High, Bariatric Surgery Candidate. Basic parameters: from 16 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Individualized High Positive End-expiratory Pressure on Postoperative Pulmonary Rate in Laparoscopic Bariatric Surgeries
Overview
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications
Interventions
- Other titated PEEP to best static compliance
the Intraoperative PEEP will be titrated to best static compliance for each patient
Primary outcome measures
- postoperative pulmonary complication [Time frame: postoperative 10 days after surgery]
Secondary outcome measures (1)
- Pulmonary functions test [Time frame: postoperative 1st , 3rd and 5th day]
Eligibility criteria
Inclusion criteria
- Patients were eligible for participation if the met the following criteria
- Age between 18 and 60 years old.
- Body mass index > 40
- Laparoscopic bariatric elective surgery under general anesthesia.
- ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.
Exclusion criteria
- Previous lung surgery
- ASA status III or IV.
- Moderate to severe obstructive or restrictive lung disease .
- Persistant intraoperative hemodynamic instability .
- Need for postoperative mechanical ventilation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Egypt · 1 center
- Ain shams university — Cairo
Identifiers
NCT: NCT06168162 · FMASU MD259/2023