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Recruiting NCT06163300

MRI Analysis and Degenerative Spine

— Observational Spine Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MRI advanced techniques.
Who it may be relevant to
Registry conditions: Spine Disease. Basic parameters: 50 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Portugal
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Analysis of MRI advanced techniques in degenerative spinal disease. The main questions it aims to answer are: * Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease * What are the image biomarkers affected by disease * How they evolve with disease progression and treatment

Interventions

  • Diagnostic test MRI advanced techniques
    Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.

Primary outcome measures

  • ODI - Oswestry Disability Index [Time frame: 18 months]
  • Lumbar Pain Intensity [Time frame: 18 months]

Eligibility criteria

Inclusion criteria

  • Age between 50 and 85 years
  • Diagnosis of spinal disease by clinical and imagiological criteria
  • More than 3 months duration of disease
  • Ability to give consent
  • Fluent portuguese speaker

Exclusion criteria

  • Previous spine surgery
  • Spinal instability
  • Neurological disease that might interfere with walking
  • Known orthopedic conditions that causes significant gait impairment
  • Dementia or development disorder with cognitive impairment
  • Inability to give consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Portugal · 1 center
  • Hospital da Luz Setúbal — Setúbal

Identifiers

NCT: NCT06163300 · a319_b

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗