Thrive Intervention in Schools
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: THRIVE, Parenting Wisely.
- Who it may be relevant to
- Registry conditions: Childhood Mental Disorder. Basic parameters: 3 years — 7 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Promoting Emotional Development Among Young Children Facing Adversity: An Effectiveness Implementation Study in St. Louis Schools
Overview
This study is designed to test the effectiveness and implementation of an early intervention therapy for children and their primary caregivers by using existing school counselors across several school districts. The intervention is a 6-8 week caregiver-child intervention (THRIVE) which will be conducted via video conference in the family's home (i.e., zoom), or within the school setting (or a combination of those 2 modalities depending upon feasibility for the family). THRIVE will be compared to an asynchronous on-line parenting education program, Parenting Wisely (PW). This online parenting course will be accessed at www.parentingwisely.com. Existing school counselors will be trained in the delivery of THRIVE to 3-7 year old children (in preschool, kindergarten and first grade) and their primary caregivers. In addition to testing the effectiveness of THRIVE compared to PW, we will also compare two implementation strategies: THRIVE-Coached and THRIVE-Low Coached (LC). We will assess ongoing coaching of THRIVE trainees to increase therapist efficacy and adherence to the intervention (THRIVE-Coached). This will be compared to implementation of THRIVE with low supports (e.g. weekly supervision) provided only for the first case following the initial training (THRIVE-LC\]. Compared to those randomized to PW, we expect children who receive THRIVE will have significantly better behavioral and socio-emotional outcomes. Caregivers who receive THRIVE will experience less parenting stress and depression, more optimism and will show more nurturing, emotional tolerance, and supportive caregiving. Therapists in the THRIVE-Coached condition will deliver the intervention with higher achieved outcomes and find the intervention to be more acceptable than therapists in the THRIVE-LC condition. Therapists in the THRIVE-Coached condition will be more likely to plan to sustain the intervention following the completion of the study than those in the THRIVE-LC condition. Parents and children receiving THRIVE from therapists in the THRIVE-Coached condition will have better socio-emotional outcomes than those in the THRIVE-LC and PW conditions.
Interventions
- Behavioral THRIVE
Early intervention for depression that directly targets developing affective systems and builds on the empirical literature on emotion development and prevention. - Behavioral Parenting Wisely
Online asynchronous parenting program.
Primary outcome measures
- Child Behavior Checklist [Time frame: T1 (baseline), T2 (halfway through intervention), T3 (completion of intervention) and T4 (12 weeks post intervention)]
Secondary outcome measures (4)
- The Emotion Regulation Checklist [Time frame: T1 (baseline), T3 (completion of intervention)]
- Coping with Children's Negative Emotions Scale [Time frame: T1 (baseline), T2 (halfway through intervention), T3 (completion of intervention)]
- Parenting Stress Index [Time frame: T1 (baseline), T3 (completion of intervention)]
- Parent-Child Observed Interaction Coding [Time frame: T1 (baseline), T3 (completion of intervention)]
Eligibility criteria
Inclusion criteria
- Near the clinical threshold on the Teacher or Parent Report Form
- An active primary caregiver can be identified and is available to participate in the intervention (mother, father, grandparent or any adult in this role)
Exclusion criteria
- Autism
- Major neurological disorder
- Participating in active weekly individual or family therapy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
United States · 1 center
- Early Emotional Development Program — St Louis
Publications
- Wang S, Quinones H, Miller L, Luby J, Kohl PL. Implementation climate and readiness for the THRIVE intervention in school settings: a mixed methods study. Implement Sci Commun. 2026 Jun 11. doi: 10.1186/s43058-026-01006-w. Online ahead of print. PMID 42277967
Identifiers
NCT: NCT06139874 · 202306092