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Recruiting NCT06132451

In-Hospital Detection of Elevated Blood Pressure

No phase Interventional Hypertension Blood Pressure, High

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Postponement of antihypertensive treatment.
Who it may be relevant to
Registry conditions: Hypertension, Blood Pressure, High. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Switzerland
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

In-Hospital Detection of Elevated Blood Pressure (INDEBP): Prevalence of New or Uncontrolled Hypertension and Safety of Postponement of Antihypertensive Treatment Adaption in Medical In-patients

Overview

The goal of this clinical trial is to analyse the prevalence of new or uncontrolled arterial hypertension (AHT) after hospital discharge of medical in-patients with elevated blood pressure (BP) values during hospitalisation. The main questions it aims to answer are: * Do elevated BP values during hospitalisation correspond to new or uncontrolled AHT after hospital discharge? * Is it safe to postpone adaption of antihypertensive treatment until after proper evaluation of AHT after hospital discharge? Participants will either be treated according to their physicians' decision or antihypertensive treatment adaptions will be postponed until after hospital discharge.

Interventions

  • Other Postponement of antihypertensive treatment
    Hypertensive blood pressure values in medical in-patients will not be treated during hospitalisation until confirmed by ABPM 4 weeks after hospital discharge

Primary outcome measures

  • Prevalence of persisting new or uncontrolled arterial hypertension [Time frame: 4 weeks after hospital discharge]
  • Prevalence of a combined hypertensive complication endpoint [Time frame: Until 4 weeks after hospital discharge]
  • Prevalence of a combined hypotensive complication endpoint [Time frame: Until 4 weeks after hospital discharge]
Secondary outcome measures (5)
  • Clinic blood pressure measurement in mmHg [Time frame: At baseline]
  • Research blood pressure measurement in mmHg [Time frame: At baseline]
  • Prevalence of previously unknown arterial hypertension [Time frame: At baseline]
  • Prevalence of female gender [Time frame: At baseline]
  • Prevalence of re-hospitalization for any cause [Time frame: Until 4 weeks after hospital discharge]

Eligibility criteria

Inclusion criteria

  • Patient hospitalized on the internal medicine ward for non-cardiovascular causes, i.e. patients hospitalized for conditions, which are not acutely worsened by uncontrolled AHT
  • Asymptomatic elevated BP values (defined as 140-180 mmHg systolic and/or 90-110 mmHg diastolic) on at least 2 occasions
  • Ability to understand study procedures and to provide written informed consent

Exclusion criteria

  • Hospitalization for any conditions which can be worsened by uncontrolled AHT:
  • Cerebrovascular events
  • Acute coronary syndrome
  • Acute or decompensated heart failure
  • Any condition preventing ABPM
  • Pregnant or lactating women
  • Failure to provide informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Diagnostic

Study locations

Switzerland · 1 center
  • University Hospital Basel — Basel

Identifiers

NCT: NCT06132451 · INDEBP-prospective · 2023-01566

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗