Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Visit at D90.
- Who it may be relevant to
- Registry conditions: Acute Ischemic Stroke. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
Detailed description
LMVOS is a prospective, real-world registry lasting for 22 years. A total of 8000 patients with large- or medium-vessel occlusion will be enrolled.
Interventions
- Other Visit at D90
Visits at 90±7 days after stroke onset were conducted by trained and blinded investigators, with face-to-face, telephone call or Internet access.
Primary outcome measures
- modified Rankin Scale (mRS) score [Time frame: 90±7 days]
Secondary outcome measures (11)
- Excellent functional outcome [Time frame: 90±7 days]
- Good functional outcome [Time frame: 90±7 days]
- mRS 0-3 [Time frame: 90±7 days]
- Change of National Institutes of Health Stroke Scale (NIHSS) [Time frame: 24 hours]
- Change of National Institutes of Health Stroke Scale (NIHSS) [Time frame: 7 days]
- Symptom-to-thrombolysis time (STT) [Time frame: 24 hours]
- Door-to-Needle Time [Time frame: 24 hours]
- Door-to-Puncture Time (DPT) [Time frame: 24 hours]
- Onset-to-recanalization time [Time frame: 24 hours]
- Door-to-Recanalization Time (DRT) [Time frame: 24 hours]
- Puncture-to-recanalization time [Time frame: 24 hours]
Eligibility criteria
Inclusion criteria
The clinical diagnosis is acute ischemic stroke with large- or medium- vessel occlusion (the criteria followed the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018).
Informed consent from the patient or surrogate.
Exclusion criteria
No additional exclusion criteria.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Affiliated Hospital of Southwest Medical University — Luzhou
Identifiers
NCT: NCT06125236 · SWMU202309