Shanghai Ovarian Cancer and Family Care Project
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Ovarian Cancer. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Ovarian cancer is the most lethal gynaecological malignancy, but its incidence in the general population is low. Due to the lack of effective prevention and successful screening approaches, most cases are diagnosed at advanced stages, leading to poor prognosis. In order to address the research requirements pertaining to ovarian cancer, the Shanghai Ovarian Cancer and Family Care Project was established. This initiative offers hospital-based resources for investigating ovarian cancer and high-risk populations. The project comprises an on-going ovarian cancer cohort, a high-risk population cohort, and a healthy population cohort. By leveraging these comprehensive cohorts, the project provides a unique platform for in-depth studies on the detection, prevention, early diagnosis, treatment, and prognosis of ovarian cancer.
Primary outcome measures
- Death due to ovarian cancer [Time frame: From diagnosis of ovarian cancer until October 31, 2028.]
Eligibility criteria
Participant meet the criteria for one of the following conditions:
- Patients attending the oncology department require differential diagnosis of ovarian cancer.
- Patients with known high-risk factors for ovarian cancer, such as history of ovarian cancer or BRCA-associated cancer, etc.
- Patients attending the Physical Examination Center who have normal findings on physical examination and no symptoms.
Exclusion criteria
- Individuals with evidence of another active cancer.
- Individuals who have prior bilateral oophorectomy.
- Individuals who are unwilling or unable to sign the informed consent form.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Shanghai first maternity and infant hospital — Shanghai
Publications
- Shi W, Zhang Y, Cheng S, Zhao Y, Li N, Li Y, Yang Y, Ding H, Li Z, Wang Y. Protocol of the SOCFC project: a longitudinal cohort study of ovarian cancer patients, high-risk populations, and healthy controls to identify factors and biomarkers associated with disease diagnosis and prognosis. BMC Cancer. 2025 Feb 26;25(1):355. doi: 10.1186/s12885-025-13652-9. PMID 40012035
Identifiers
NCT: NCT06118307 · KS23259