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Recruiting NCT06115252

Partnering to Enhance Emerging Adults' Response to Programs

No phase Interventional Alcohol Use, Unspecified

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Motivational Interviewing (MI).
Who it may be relevant to
Registry conditions: Alcohol Use, Unspecified. Basic parameters: 18 years — 19 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Partnering to Enhance Emerging Adults' Response to Programs (PEER)

Overview

The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time. Eligible youth will be invited to come in for a "Participation Day," during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.

Interventions

  • Behavioral Motivational Interviewing (MI)
    Motivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior c

Primary outcome measures

  • Blood oxygen level dependent (BOLD) response synchrony [Time frame: Baseline]
  • BOLD response synchrony association with behavior change (past month alcohol use days) [Time frame: 12 Months]
Secondary outcome measures (2)
  • BOLD response synchrony association with behavior change (past month alcohol use days) [Time frame: 3 Months]
  • BOLD response synchrony association with behavior change (past month alcohol use days) [Time frame: 6 Months]

Eligibility criteria

Inclusion criteria

  • within the specified age range
  • agree to be contacted for the 3, 6, and 12 month follow ups
  • provide fully informed consent

Exclusion criteria

  • left-handed
  • evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics)
  • loss of consciousness ≥ 2 minutes
  • other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

United States · 1 center
  • University of Texas Dallas — Dallas

Publications

  • Feldstein Ewing SW, Dash GF, Hudson KA, Hyun B, Yang M, Stahl L, Thomsen KR, Filbey FM. The Protocol for: Do peers enhance behavior change in group motivational interviewing? A translational clinical trial investigating brain synchrony in underage emerging adults during an fMRI hyperscanning task and association with alcohol use reductions. PLoS One. 2026 Jun 11;21(6):e0349575. doi: 10.1371/journa PMID 42275392

Identifiers

NCT: NCT06115252 · O25-013-1 · 1R01AA030678-01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗