Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: training strategy with adaptation of training strategies to the ANS, training strategy (standard practice).
- Who it may be relevant to
- Registry conditions: Acute Coronary Syndrome. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability: A Controlled and Randomized Study
Overview
Cardiac readaptation aims to mitigate cardiovascular risks and enhance the quality of life among coronary patients. Our research laboratory has an international expertise in training optimization in top-athletes and a previous study has demonstrated the efficacy of optimizing cardiac rehabilitation through the power-force-velocity profile (PFVP). The findings exhibited significant improvements in aerobic capacity, muscular strength, and cardiovascular parameters among patients who were trained based on their PFVP. Guided training utilizing heart rate variability (HRV) is also garnering increasing interest as a means to optimize training load and promote recovery
Detailed description
Our study aims to evaluate the application of HRV in regulating training load based on fatigue levels in cardiac rehabilitation patients utilizing the PFVP framework.
Interventions
- Other training strategy with adaptation of training strategies to the ANS
a training strategy for subjects whose PFVP is in favour of strength or speed with training load adjusted according to SNA - Other training strategy (standard practice)
a training strategy for subjects whose PFVP is in favour of strength or speed
Primary outcome measures
- The root mean square of successive differences in heart rate or RMSSD [Time frame: Baseline to 2 months]
Secondary outcome measures (10)
- Value of maximum oxygen consumption [Time frame: Baseline to 2 months]
- Assessment of the ANS sympathetic branch [Time frame: Baseline to 2 months]
- Assessment of the ANS parasympathetic branch [Time frame: Baseline to 2 months]
- non-invasive measurement of arterial stiffness [Time frame: Baseline to 2 months]
- measurement of upper and lower limb muscle strength [Time frame: Baseline to 2 months]
- assessment of PFVP evolution [Time frame: Baseline to 2 months]
- assessment of physical a activity and sedentary behavior [Time frame: Baseline to 2 months]
- quality of life assessment [Time frame: Baseline to 2 months]
- assessment of subjective fatigue [Time frame: Baseline to 2 months]
- biological data [Time frame: Baseline to 2 months]
Eligibility criteria
Inclusion criteria
- >18
- Acute Coronary Syndrome treated in the last 6 months
- Medical revascularization (angioplasty ± stenting) or surgical (coronary artery bypass)
- Initial CPETt: MPA ≥ 60w in women and ≥80w in men
- French
- Informed consent
Exclusion criteria
\- Significant co-morbidities limited practice of physical activity
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Other
Study locations
France · 1 center
- Chu Saint-Etienne — Saint-Etienne
Identifiers
NCT: NCT06107452 · 23CH152 · 2023-A01452-43