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Enrolling by invitation NCT06105866

Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion

Observational The Relationship Between TAPSE Value and Volume

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Tricuspid Annular Plane Systolic Excursion.
Who it may be relevant to
Registry conditions: The Relationship Between TAPSE Value and Volume. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion (TAPSE)

Overview

The aim of our study is to try to establish a relationship between preoperative fasting-related volume changes and tricuspid annular plane systolic excursion (TAPSE), and to determine whether there are changes in right ventricular functions due to preoperative fasting.

Detailed description

TAPSE (Tricuspid Annular Plane Systolic Excursion) is a parameter that easily measures apex-base shortening and provides specific information about global right ventricular (RV) function. It is less dependent on optimal image quality and serves as an easily measurable criterion compared to other RV function measurements. In this study, one day before the operation, transthoracic echocardiography (TTE) will be conducted on fasting patients, and if the preoperative fasting duration is appropriate on the day of the surgery, TTE measurements will be repeated and recorded. The study aims to evaluate the relationship between TAPSE and volume and determine whether there are any changes in right ventricular functions due to preoperative fasting.

Interventions

  • Diagnostic test Tricuspid Annular Plane Systolic Excursion
    Transthoracic echocardiography will be performed on patients during hospitalization and preoperatively to investigate the relationship between preoperative fasting and right ventricular functions. This will be examined by looking at TAPSE

Primary outcome measures

  • The TAPSE value is related to volume [Time frame: Patients who apply to our hospital for surgery within 6 months will be included in our study. Preoperative TAPSE measurements will be taken from the patients twice, first during admission and immediately before the operation]

Eligibility criteria

Inclusion criteria

  • ASA 1-2-3
  • The patient must be between 18 and 75 years old.
  • Perioperative hydration has not been administered.
  • Preoperative sedatives have not been given.
  • There should be no known heart disease.

Exclusion criteria

  • The patient being pregnant
  • Post-cardiac surgery
  • Severe pulmonary hypertension
  • Severe valve disease
  • Hypertrophic or dilated cardiomyopathy
  • Presence of acute myocardial infarction
  • Non-sinus rhythm

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Turkey (Türkiye) · 1 center
  • Sevil Gulasti — Aydin

Publications

  • Lee S, Kamdar F, Madlon-Kay R, Boyle A, Colvin-Adams M, Pritzker M, John R. Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function. J Heart Lung Transplant. 2010 Feb;29(2):209-15. doi: 10.1016/j.healun.2009.11.599. PMID 20113911
  • Gullupinar B, Saglam C, Koran S, Turhan A, Unluer EE. The role of mitral annular plane systolic excursion in prediction of acute blood loss in healthy voluntary blood donors. J Ultrason. 2022 Feb 8;22(88):e33-e38. doi: 10.15557/JoU.2022.0006. eCollection 2022 Mar. PMID 35449700
  • Zhang H, Wang X, Chen X, Zhang Q, Liu D. Tricuspid annular plane systolic excursion and central venous pressure in mechanically ventilated critically ill patients. Cardiovasc Ultrasound. 2018 Aug 7;16(1):11. doi: 10.1186/s12947-018-0130-2. PMID 30081914
  • Newman K, Wilson R, Roberts JM, Mayo JR, Mohamed Ali AA, Brunner N, Sedlic A. Tricuspid annular plane systolic excursion for the evaluation of right ventricular function in functional cardiac CT compared to MRI. Clin Radiol. 2021 Aug;76(8):628.e1-628.e7. doi: 10.1016/j.crad.2021.02.018. Epub 2021 Apr 18. PMID 33879320

Identifiers

NCT: NCT06105866 · NCT093509350935

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗