EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Dose escalated resistance training.
- Who it may be relevant to
- Registry conditions: Cancer. Basic parameters: 20 years — 89 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
EXERT-C: Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer
Overview
This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.
Interventions
- Other Dose escalated resistance training
All individuals will be engaging in resistance training during and/or after their cancer treatment
Primary outcome measures
- Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis [Time frame: 3 months]
- Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound [Time frame: 3 months]
- Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen [Time frame: 3 months]
Secondary outcome measures (4)
- Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen [Time frame: 3 months]
- Determine changes in Y-balance score for each leg [Time frame: 3 months]
- Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen [Time frame: 3 months]
- Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Age 20-89 years
- Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study.
- Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI
- Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.
- Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere
Exclusion criteria
1\. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- AHN CI Exercise Oncology and Resiliency Center — Pittsburgh
Publications
- Champ CE, Carpenter DJ, Diaz AK, Rosenberg J, Ackerson BG, Hyde PN. Resistance Training for Patients with Cancer: A Conceptual Framework for Maximizing Strength, Power, Functional Mobility, and Body Composition to Optimize Health and Outcomes. Sports Med. 2023 Jan;53(1):75-89. doi: 10.1007/s40279-022-01759-z. Epub 2022 Sep 29. PMID 36175646
Identifiers
NCT: NCT06083324 · 2023-021-SG