Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Robotic right hemicolectomy, Laparoscopic right hemicolectomy.
- Who it may be relevant to
- Registry conditions: Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Benign, Colorectal Cancer. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Robotic Right Hemicolectomy With Intracorporeal Anastomosis Versus Laparoscopic Right Hemicolectomy With Extracorporeal Anastomosis (PRORHEM): a Randomized Controlled Trial
Overview
Robotic right hemicolectomy with intra-corporeal anastomosis may have better short-term recovery outcomes and decreased incidence of incisional hernia when compared to the laparoscopic actual standard of care, for similar safety outcomes.
Detailed description
During laparoscopic right hemicolectomy (lapRHC) for cancer or polyp, intra-corporeal anastomosis (ICA) offers better short-term recovery and decreased incidence of incisional hernia (IH) when compared to extra-corporeal anastomosis (ECA). However, because of the technical limitations of laparoscopy, ICA has not gained in wide acceptance and ECA has remained the standard of care. On the contrary, robotics offers improved suturing capacities and facilitates the realization of ICA. Therefore, robotic right hemicolectomy (robRHC) with ICA may have better short-term recovery outcomes and decreased incidence of IH when compared to the laparoscopic actual standard of care. In a randomized controlled trial, we will compare robRHC with ICA with lapRHC with ECA, in terms of recovery of bowel function (time to first passage of faeces). Secondary outcomes will notably include length of stay, incidence of IH, patient-reported esthetical outcomes and safety outcomes (morbidity, mortality, proximal and distal margins, harvested lymph nodes).
Interventions
- Procedure Robotic right hemicolectomy
Robotic right hemicolectomy with intracorporeal anastomosis and extraction through a C-section, using the Da Vinci Xi. - Procedure Laparoscopic right hemicolectomy
Laparoscopic right hemicolectomy with extracorporeal anastomosis and extraction through midline.
Primary outcome measures
- Time to first passage of faeces [Time frame: From index surgical procedure (skin closure) until time of first passage of faeces, during hospitalisation, on average during the first 7 post-operative days]
Secondary outcome measures (12)
- Duration of surgery [Time frame: From skin incision to skin closure, during index surgical procedure]
- Blood loss [Time frame: From skin incision to skin closure, during index surgical procedure]
- Intra-operative transfusion [Time frame: From skin incision to skin closure, during index surgical procedure]
- Intra-operative complication [Time frame: From skin incision to skin closure, during index surgical procedure]
- Conversion to open surgery [Time frame: From skin incision to skin closure, during index surgical procedure]
- Length of the extraction site [Time frame: At post-operative day 30]
- Creation of a stoma [Time frame: From skin incision to skin closure, during index surgical procedure]
- Hb, WBC and CRP [Time frame: At post-operative day 1, post-operative day 2, post-operative day 3, post-operative day 4 and post-operative day 5]
- Time to first passage of flatus [Time frame: From index surgical procedure (skin closure) until time of first passage of flatus, during hospitalisation, on average during the first 7 post-operative days]
- In-hospital postoperative ileus [Time frame: During hospitalisation, on average during the first 5 post-operative days]
- Length of stay [Time frame: From the first day of hospitalisation to the day of discharge, on average during the first 10 post-operative days]
- Post-operative morbidity [Time frame: From index surgical procedure (skin closure) to post-operative day 30]
Eligibility criteria
Inclusion criteria
- Adult patients requiring elective minimally invasive RHC for cT1-T3 Nx M0 cancer of the right colon (including cancer of the appendix, caecum, ascending colon and hepatic flexure).
Exclusion criteria
- Not scheduled for minimally invasive RHC (refuses surgery and/or planned open approach)
- Emergency surgery
- Hereditary colorectal cancer
- Inflammatory bowel disease
- Synchronous resection of (an)other organ(s)
- Synchronous surgical procedure (including more extended resection of the lower gastrointestinal tract)
- cT4
- cM+
- History of laparotomy
- Pregnancy
- No anastomosis planned
- Unable to provide informed consent
- No informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Meyer J, Liot E, Meurette G, Toso C, Ris F. Robotic right hemicolectomy with intracorporeal anastomosis versus laparoscopic right hemicolectomy with extracorporeal anastomosis (PRORHEM): protocol for a randomized controlled trial. BMC Surg. 2026 Jul 8. doi: 10.1186/s12893-026-03990-1. Online ahead of print. PMID 42420958
Identifiers
NCT: NCT06067620 · PRORHEM