Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sub Acute Whole Body Vibration Training.
- Who it may be relevant to
- Registry conditions: Whole Body Vibration, Osteo Arthritis Knee. Basic parameters: 40 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Pilot Investigation on the Effects of Sub Acute (12 Week) Home Base Whole-body Vibration Training in Osteoarthritis.
Overview
The purpose of this proposal is to understand how the Vibrant Health Ultimate whole-body vibration (WBV) machine affects pain and inflammation in older adults. The investigators' hypothesize that sub-acute (12 weeks) WBV will lead to improvement in the level of knee pain and improve vascular function via a decrease in systemic inflammation.
Detailed description
Knee osteoarthritis (KO) is a leading cause of disability and medical cost. Whole body vibration (WBV) has emerged as an exercise alternative that may be more tolerable than traditional forms of exercise, such as treadmill walking/running or cycling. Similar to traditional exercise, research supports that WBV can be very beneficial for your health. In fact, a single bout of WBV increases circulating concentrations of inflammatory markers. WBV is safe and effective, WBV training has been conducted in obesity, elderly, patients with diabetes, patients with lung disease, as well as patients with knee osteoarthritis.
Interventions
- Device Sub Acute Whole Body Vibration Training
Participants will be given a personal vibration plate (equipped with stabilizing bars) to take home for training which will last for up 12 weeks. For this test the participant will be asked to stand on a vibration plate for up to 20 minutes. Participants will be instructed to remove any footwear and stand mid-center on the platform in a standing position with feet shoulder width apart. The participant will be asked to step on and off of the vibration plate. During the first four weeks, participa
Primary outcome measures
- Change in Pain Pressure Threshold assessed using the Jtech Medical Echo Algometer [Time frame: pre-treatment baseline and following 12 weeks sub-acute whole-body vibration]
Secondary outcome measures (2)
- Change in Pulse Wave Velocity (PWV) [Time frame: pre-treatment baseline and following 12 weeks sub-acute whole-body vibration]
- Change in IL-6 [Time frame: pre-treatment baseline and following 12 weeks sub-acute whole-body vibration]
Eligibility criteria
Inclusion criteria
- Symptomatic Osteoarthritic knee pain for at least 6 months.
- Mean and women
- Ages 40-75 years old
Exclusion criteria
- <40 years old or >75 years old
- History of balance issues
- History of falls
- Epilepsy
- Pregnancy
- The use of whole-body vibration in the past 6 months
- Previous knee surgery within last 3 years
- Unable to stand for at least 20 minutes (for whole body vibration training)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
United States · 1 center
- Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Ph — Augusta
Identifiers
NCT: NCT06058169 · 2054289