Recruiting NCT06050447
Factors Affecting the Results of Treatment of Patients With Colorectal Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Right hemicolectomy, Left hemicolectomy, Sigmoid colon resection, Anterior resection of the rectum.
- Who it may be relevant to
- Registry conditions: Colorectal Cancer, Colon Cancer, Rectal Cancer, Colorectal Adenocarcinoma. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Russia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The study attempts to quantify the relative risks for mortality, anastomotic leakage and other early and late postoperative complications, recurrence rate, cancer-specific survival, recurrence-free survival after colorectal surgery for patients with colorectal cancer depending on the localization of the tumor.
Interventions
- Procedure Right hemicolectomy
Resection of the caecum and ascending colon is appropriate for patients with tumors located anywhere from caecum to the transverse colon - Procedure Left hemicolectomy
Resection of the sigmoid colon is appropriate for patients with tumors located anywhere from the distal transverse colon to the rectosigmoid junction. - Procedure Sigmoid colon resection
Resection of the sigmoid colon is appropriate for patients with tumors located in the sigmoid colon - Procedure Anterior resection of the rectum
AR is appropriate for tumors located in rectosigmoid junction and in the proximal rectum - Procedure Low anterior resection of the rectum
LAR is appropriate for tumors located in the middle and low rectum - Procedure Abdominoperineal resection
APR is appropriate for distal rectal cancers that invade the external sphincter or the levator muscles - Procedure Total Colectomy
Total abdominal colectomy may be indicated for patients with primary multiple cancer tumors
Primary outcome measures
- Anastomotic leakage rate [Time frame: 3 months after surgery]
- Mortality rate [Time frame: 3 years after surgery]
Secondary outcome measures (4)
- 30-day complication rate [Time frame: 30 days after surgery]
- Recurrence rate [Time frame: 3 years after surgery]
- Cancer-specific survival [Time frame: 3 years after surgery]
- Recurrence-free survival [Time frame: 3 years after surgery]
Eligibility criteria
Inclusion criteria
- Histologically proven primary adenocarcinoma of bowel;
- All patients who have indications for surgical treatment of colorectal cancer based on the decision of the oncological council;
- Signed informed consent with agreement to attend all study visits;
Exclusion criteria
- Unresectable tumor or contradictions to surgery;
- Indications for chemotherapy or radiation therapy prior to surgery;
- Patient withdrawal from the trial or loss of follow-up;
- Emergent operation;
- Pregnancy.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Russia · 1 center
- Baltic Federal University — Kaliningrad
Identifiers
NCT: NCT06050447 · 5995465480