Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: nutrition, IYCF, WASH education, scheduled anthropometric screening, family MUAC.
- Who it may be relevant to
- Registry conditions: Severe Acute Malnutrition, Moderate Acute Malnutrition. Basic parameters: 6 months — 59 months · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Ethiopia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Efficacy and Safety of Family Mid-upper Arm Circumference (MUAC) After Recovery From Severe and Moderate Acute Malnutrition
Overview
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. For the Family MUAC follow-up study, children who recover from these two parallel clinical trials will be enrolled in trial to test the effectiveness of MUAC screening at home by the child's caregivers as a self-referral strategy, compared to a scheduled health facility-led strategy and the standard of care of community-based follow-up visits.
Interventions
- Other nutrition, IYCF, WASH education
nutrition, IYCF, WASH education - Other scheduled anthropometric screening
anthropometric screening by health care workers at 1, 3, and 6 months - Other family MUAC
family MUAC training for the primary caregiver present at the time of recovery
Primary outcome measures
- number of episodes of relapse to acute malnutrition identified [Time frame: 6 months]
Secondary outcome measures (7)
- weight-for-height Z-score (WHZ) at time relapse to acute malnutrition identified [Time frame: 6 months]
- mid-upper arm circumference (MUAC) at time relapse to acute malnutrition identified [Time frame: 6 months]
- number of episodes of relapse to edematous malnutrition / kwashiorkor identified [Time frame: 6 months]
- recovery rates following treatment of relapse to acute malnutrition [Time frame: 6 months]
- mortality [Time frame: 6 months]
- hospitalization [Time frame: 6 months]
- loss to follow-up [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- children 6-59 months of old who recovered from SAM or MAM following treatment in either the MODAM-SAM or MODAM-MAM trials
Exclusion criteria
- caregiver not planning on remaining in the local area for the subsequent 6 months
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Diagnostic
Study locations
Ethiopia · 3 centers
- Sekota — Sekota
- Teltele — Teltelē
- Gode — Gode
Publications
- Trehan I, Beyene Y, Darsene H, Adams BS, Wrabel M, Gizaw G, Legese LA, Cichon B, Chitekwe S, Shellemew MW, Tessema M, Stobaugh HC. The Modified Dosages for Acute Malnutrition (MODAM) study: protocol for three integrated randomized controlled trials of novel approaches for the management of childhood wasting in Ethiopia. BMC Nutr. 2025 Apr 8;11(1):71. doi: 10.1186/s40795-025-01054-w. PMID 40200326
Identifiers
NCT: NCT06038071 · MODAM-fMUAC