Menu
Recruiting NCT06017518

An Observational Study of Local Relapse After High Grade Osteosarcoma

— Observational Osteosarcoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Osteosarcoma. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

multicenter retrospective and prospective study in patients with high-grade osteosarcoma

Detailed description

This is a multicenter retrospective and prospective study that will analyze all cases with of diagnosis of local relapse in high-grade osteosarcoma from 01 January 1980 and all new cases referring to each participant site.

Primary outcome measures

  • post local relapse survival [Time frame: 24 months follow up]

Eligibility criteria

Inclusion criteria

  • Patients who experienced LR as first event of recurrence after treatment for localized high-grade osteosarcoma of bone, including cases with synchronous lung metastases
  • Adequate patient compliance to follow-up visits
  • Written informed consent prior to any study-specific analysis and/or data collection
  • No age limits

Exclusion criteria

  • Cases of LR demonstrated after > 3 months after metastatic disease
  • Impossibility to ensure adequate compliance

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-control

Study locations

Italy · 2 centers
  • IRCCS Istituto Ortopedico Rizzoli — Bologna
  • Azienda Ospedaliero-Universitaria Pisana — Pisa

Identifiers

NCT: NCT06017518 · OSTEO LR

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗