Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: observational prospective data collection.
- Who it may be relevant to
- Registry conditions: Post Intensive Care Syndrome. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS). Other complications have been described, including ICU-acquired weakness, leading to increased morbidity and mortality after discharge. Actually, risk factors associated with post-ICU fatigue self-reported are not really known.
Detailed description
Frailty, defined as a decrease in physiological reserves leading to an alteration in the mechanisms of adaptation to stress, increases the incidence of PICS and could therefore be a cause of post-ICU fatigue self-reported.
The aim of this study is to identify a relationship between markers of frailty, ICU-AW, ICU story and the post-ICU fatigue self-reported 6 months discharge in patients with prolonged ICU stays.
Interventions
- Other observational prospective data collection
Collection of data from medical records.
Primary outcome measures
- Frailty [Time frame: 1 year]
Secondary outcome measures (4)
- Fatigue [Time frame: 1 year]
- ICU-acquired weakness and fatigue [Time frame: 1 year]
- Fatigue, quality of life, anxiety and depressive disorder [Time frame: 1 year]
- Kinetic of muscle mass loss and post-ICU fatigue self-reported [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- Patients with a length of stay in intensive care > or equal to 7 days, or mechanical ventilation > or equal to 5 days
Exclusion criteria
- Scheduled surgery with admission in ICU
- Pregnancy
- Guardianship
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 2 centers
- Chu Saint-Etienne — Saint-Etienne
- Hôpital Privé de la Loire — Saint-Etienne
Identifiers
NCT: NCT05984069 · IRBN962022/CHUSTE