HD-tDCS to Modulate Connectivity
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: high definition transcranial direct current stimulation (HD-tDCS).
- Who it may be relevant to
- Registry conditions: Electricity; Effects. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Canada
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Modulating Functional Brain Connectivity Using High Definition Transcranial Direct Current Stimulation (HD-tDCS)
Overview
The purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further improved.
Detailed description
Normal healthy individuals will be recruited and undergo a standardized neuropsychological assessment (ANAM, MoCA, BDI-II, ToMS, and MAAS) and magnetic resonance imaging (MRI). During MRI, HD-tDCS will be applied. Four different stimulation targets will be investigated, and subjects will be randomly assigned for each target groups or sham group. After HD-tDCS/MRI session, subjects will be re-assessed with standardized neuropsychological tests.
Interventions
- Device high definition transcranial direct current stimulation (HD-tDCS)
HD-tDCS will be provided for 20 minutes for each stimulation with peak intensity of 2mA.
Primary outcome measures
- change of functional connectivity [Time frame: 0-11 minutes after the stimulation contrasting baseline (before stimulation)]
Secondary outcome measures (3)
- change of cerebral blood flow [Time frame: 12-16 minutes after the stimulation contrasting baseline (before stimulation)]
- Toronto Mindfulness Scale (curiosity) [Time frame: Baseline, then within 1-2 hours from stimulation]
- Toronto Mindfulness Scale (decentering) [Time frame: Baseline, then within 1-2 hours from stimulation]
Eligibility criteria
Inclusion criteria
\- All other than excluded.
Exclusion criteria
- History or susceptibility to any neurological or psychiatric diseases, particularly seizures
- abnormal MRI
- metal implants or a cardiac pacemaker
- pregnant or breastfeeding women
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Basic science
Study locations
Canada · 1 center
- University of Manitoba — Winnipeg
Identifiers
NCT: NCT05959551 · HS24853