A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Echocardiography.
- Who it may be relevant to
- Registry conditions: Anesthesia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Changes in Loading Conditions on Induction of General Anesthesia: Mechanisms of Post-Induction Hypotension (PIH)
Overview
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.
Interventions
- Diagnostic test Echocardiography
Echocardiography and Clearsight BP measurements before, immediately after anesthesia induction and after intubation (for 20 min)
Primary outcome measures
- The proportion of patients with post-induction hypotension (PIH) [Time frame: up to 20-mins after anesthesia induction.]
Eligibility criteria
Inclusion criteria
- Adult patients ≥ 18 years of age requiring general anesthesia for surgery
- Intubation required for anesthetic management / surgery
- Anticipated prep time before incision of 20 minutes
- Baseline MAP >70mmHg
Exclusion criteria
- History of coronary artery disease
- History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
- History of peripheral artery occlusive disease
- Beta-blocker use
- Anti-hypertensive medication use
- Patients with epidural, spinal, paravertebral, serratus blocks preoperatively
- Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)
- Emergency surgery
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Memorial Sloan Kettering Cancer Center (All protocol activites) — New York
Identifiers
NCT: NCT05954832 · 23-079