Buccal Mucosal Graft for Onlay Ureteroplasty in the Management of Proximal Ureteral Stricture
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Buccal mucosa for proximal ureter stricture.
- Who it may be relevant to
- Registry conditions: Stricture Ureter. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Onlay uretroplasty with either grafts or flaps has been attempted by many reconstructive urologists, ln particular buccal mucosa graft (BMG) ureteroplasty has been reported by many centers and has shown its feasibility and safety
Detailed description
In cases of long segment upper ureteral stricture, more advanced surgical techniques, such as renal mobilization and downward nephropexy, ileal ureter replacement, transureteroureterostomy, and autotransplantation of the kidney, are necessary to provide a tension-free anastomosis.
Autotransplantation of the kidney needs more efforts, more experts and may lead to significant renovascular complications.
Also, there is severe metabolic and intestinal complications are associated with using of long intestinal segment in the management of ureteral stricture \[9\].
These previous side effects and difficulties make the management of long upper and middle ureteral strictures more complicated and indicate other lines of management urgently.
Even the ureteral stricture still not patent enough to drain urine but still, we can use it as a ureteral plate with little affection of its vascularity. Based on this theory an onlay repair technique was emerged.
Onlay uretroplasty with either grafts or flaps has been attempted by many reconstructive urologists, ln particular buccal mucosa graft (BMG) ureteroplasty has been reported by many centers and has shown its feasibility and safety.
Interventions
- Procedure Buccal mucosa for proximal ureter stricture
Patients with inclusion criteria of uretral stricture will be treated with open uretroplasty with buccal graft and omental wrapping
Primary outcome measures
- Restoration of ureteric patency. [Time frame: 6 months post-operative]
Secondary outcome measures (1)
- Pain relief after surgery [Time frame: 6 months post-operative]
Eligibility criteria
Inclusion criteria
- Proximal ureteral stricture or uretropelvic junction obstruction (UPJO) which are not amenable for primery anastmosis.
Exclusion criteria
- Buccal graft contraindications as i. Active oral infections ii.Oral cancers like cancers of lips, tongue or cheeks.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Urology department - AlAzhar university — Cairo
Identifiers
NCT: NCT05928364 · Buccal graft ureteroplasty