Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: observation.
- Who it may be relevant to
- Registry conditions: Heat Stroke. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke. The main questions it aims to answer are: * the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke. * the best body temperature at the cutting point of stop cooling. * The relationship between the volume and speed of ice saline infusion and the cooling effect.
Interventions
- Other observation
This study is an observational study. Patients will receive conventional cooling measures and organ function support.
Primary outcome measures
- mortality [Time frame: up to 90 days]
- organ damage [Time frame: up to 90 days]
Secondary outcome measures (3)
- continuous renal replacement therapy [Time frame: up to 90 days]
- length of ICU stay [Time frame: up to 90 days]
- length of hospital stay [Time frame: up to 90 days]
Eligibility criteria
Inclusion criteria
- ≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.
Exclusion criteria
- need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
China · 6 centers
- Yiwu Central Hospital — Yiwu
- Dongyang People's Hospital — Dongyang
- The Second Affiliated Hospital of Zhejiang University School of Medicine — Hangzhou
- Jinhua Municipal Central Hospital — Jinhua
- Jinhua People's Hospital — Jinhua
- Lanxi People's Hospital — Lanxi
Identifiers
NCT: NCT05921682 · 2023-0517