Gait Control in Parkinson Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Walking test, Disease assessement.
- Who it may be relevant to
- Registry conditions: Parkinson Disease. Basic parameters: 18 years — 99 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Belgium
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Flexible Control of Gait in Parkinson Disease: Effect of Task Instruction on the Exploitation of Redundancy in Speed Control.
Overview
Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.
Interventions
- Other Walking test
Walk with and without a metronome - Other Disease assessement
Disease stage assessed by a doctor
Primary outcome measures
- Stride cadence [Time frame: Measured during the entire experiment (an average of 4.5 years)]
- Stride amplitude [Time frame: Measured during the entire experiment (an average of 4.5 years)]
Eligibility criteria
Inclusion criteria
- Patients and volunteers able to walk for 20mins and without other neurological disorders.
Exclusion criteria
- Patients or volunteers unable to walk for 20mins and with other neurological disorders.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
Belgium · 1 center
- Université catholique de Louvain — Louvain-la-Neuve
Identifiers
NCT: NCT05908279 · GAIT-PD