Health ImprOvement Program of Bone in China
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Regular follow-up.
- Who it may be relevant to
- Registry conditions: Osteoporosis. Basic parameters: 40 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Fracture risk factors have long been identified as key factors in osteoporosis and fragility fractures. The WHO recommended Fracture risk assessmenttool (FRAX) applies clinical risk factors to assess the absolute risk of osteoporotic fractures in each individual. Our preliminary study suggests that FRAX estimates may underestimate the risk of fractures in the Chinese population. In order to optimize the risk prediction model of osteoporotic fractures, a treatment threshold and its optimal cutting point were initially established based on the data of the health management Center of the Second Xiangya Hospital of Central South University.
Interventions
- Other Regular follow-up
Follow-up of the population was conducted to track the incidence of fractures
Primary outcome measures
- bone mineral density bone mineral density [Time frame: From 2021 to 2031]
- Occurrence of fracture [Time frame: From 2021 to 2031]
- clinical risk factors of osteoporotic fracture [Time frame: From 2021 to 2031]
Eligibility criteria
Inclusion criteria
- Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent
Exclusion criteria
- Under 40 years of age， Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Health Management Center, The Second Xiangya Hospital of Central South University — Changsha
Publications
- Yue C, Li YF, Xu LL, Wang QY, Yang YY, Sheng ZF. Develop a bone mineral density T-score distribution nomograms based on osteoporosis risk factors for middle-aged and older adults. Geriatr Nurs. 2024 Jul-Aug;58:344-351. doi: 10.1016/j.gerinurse.2024.06.010. Epub 2024 Jun 13. PMID 38875761
Identifiers
NCT: NCT05906147 · LYF2021015.