Prehabilitation Effect on Function and Patient Satisfaction Following Total Knee Arthroplasty
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Maximal strength training.
- Who it may be relevant to
- Registry conditions: Prehabilitation, Knee Osteoarthritis. Basic parameters: 50 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Norway
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Knee arthrosis has a high prevalence. Non-surgical treatment, such as exercise, is the first choice of treatment. However, most patients end up having a surgical procedure such as total knee arthroplasty. Following surgery with total knee replacement as much as 20% of patients report to not be satisfied with the results. It is noteworthy that this level of dissatisfaction has persisted over the last decades despite formidable progress in surgical methods and technology. Leg strength prior to surgery is associated with faster recovery post operatively, which may influence satisfaction. The investigators aim is to implement a period of strength training prior to surgery to evaluate if training prior to surgery may reduce the level of dissatisfaction post operatively.
Interventions
- Behavioral Maximal strength training
3 sessions/ week. leg press at \~85% of one repetition maximum for 8 weeks
Primary outcome measures
- Change in Leg press strength [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.]
- Group differences in Patient satisfaction [Time frame: Change from 3 week post-surgery, 12 months post-surgery.]
Secondary outcome measures (5)
- Change in Voluntary activation [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery.]
- Change in Self reported knee function [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.]
- Change in Walking speed [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.]
- Change in Chair rising ability [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.]
- Change in Balance [Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.]
Eligibility criteria
Inclusion criteria
- Knee artrosis, refered to surgery
Exclusion criteria
- Kognitive disability
- Inflamatory disease in muscles
- varus/ valgus and extension deficit >15 degrees
- Neurological disorders
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
Norway · 1 center
- Molde University College — Molde
Publications
- Izadi M, Toien T, Ohrn FD, Schnell Husby O, Kvitland Schnell Husby V, Bjorgen Winther S, Sherman R, Forsberg Brobakken M, Wang E, Berg OK. Effects of preoperative maximal strength training on muscle strength and function in total knee arthroplasty: A randomized controlled trial. Ann Phys Rehabil Med. 2026 Mar;69(2):102067. doi: 10.1016/j.rehab.2025.102067. Epub 2026 Jan 13. PMID 41534474
Identifiers
NCT: NCT05892133 · 522685