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Recruiting NCT05868161

Pounce™ Thrombectomy System Retrospective Registry

Observational Peripheral Arterial Disease Acute Limb Ischemia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Pounce Thrombectomy System.
Who it may be relevant to
Registry conditions: Peripheral Arterial Disease, Acute Limb Ischemia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The PROWL registry is an open-label retrospective, multi-center, US study of the Surmodics™ Pounce™ Thrombectomy System for the non-surgical removal of emboli and thrombi in the peripheral arterial vasculature.

Interventions

  • Device Pounce Thrombectomy System
    Non-surgical removal of thrombi and emboli from the peripheral arterial vasculature with the Pounce Thrombectomy System.

Primary outcome measures

  • Procedural Success [Time frame: Peri-procedural (by the end of the index procedure)]
  • Incidence of device related Major Adverse Events (MAEs) [Time frame: Procedure to 30 days]
Secondary outcome measures (12)
  • Technical success [Time frame: Peri-procedural (by the end of the index procedure)]
  • Completeness of thromboemboli removal (by angiography) [Time frame: Peri-procedural (by the end of the index procedure)]
  • Thrombo-aspiration in Peripheral Interventions (TIPI) flow rate [Time frame: Peri-procedural (by the end of the index procedure)]
  • Modified Society for Vascular Surgery (SVS) runoff [Time frame: Pre-procedure, Peri-procedural (by the end of the index procedure)]
  • Underlying atheroma stenosis [Time frame: Peri-procedural (by the end of the index procedure)]
  • Describe index procedural characteristics [Time frame: Peri-procedural (by the end of the index procedure)]
  • Adjunctive procedures [Time frame: Peri-procedural (by the end of the index procedure)]
  • Index procedure durations [Time frame: Peri-procedural (by the end of the index procedure)]
  • Characterize subject index procedure hospitalization course at discharge [Time frame: Index procedure hospital admission to discharge, approximately 1 to 2 days]
  • Characterize subject index procedure hospitalization course at discharge [Time frame: Index procedure hospital admission to discharge, approximately 1 to 2 days]
  • Characterize subject index procedure hospitalization course at discharge [Time frame: Index procedure hospital admission to discharge, approximately 1 to 2 days]
  • Characterize subject index procedure hospitalization course at discharge [Time frame: Index procedure hospital admission to discharge, approximately 1 to 2 days]

Eligibility criteria

Inclusion criteria

  • Subject underwent an endovascular intervention where the Pounce Thrombectomy System was attempted
  • Subject is willing and able to provide informed consent prior to the collection of study data or a consent waiver is in place

Exclusion criteria

  • Subject is under the age of 18 years

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 9 centers
  • OSF St. Francis Medical Center — Peoria
  • Community Hospital — Munster
  • Baton Rouge General Medical Center — Baton Rouge
  • Allina Health — Minneapolis
  • Cleveland Clinic — Cleveland
  • Prisma Health Upstate — Greenville
  • North Central Heart — Sioux Falls
  • Vanderbilt University Medical Center — Nashville
  • … and 1 more center

Identifiers

NCT: NCT05868161 · SUR22-001

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗