Menu
Recruiting NCT05864638

Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study

— Observational Acute Ischemic Stroke Large Vessel Occlusion Thrombectomy Thrombosis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Endovascular treatment.
Who it may be relevant to
Registry conditions: Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study （OCIN-AIS-EVT REGISTRY）

Overview

A Multicenter Registry of Endovascular Treatment for Acute Ischemic Stroke.

Detailed description

The OCIN-AIS-EVT REGISTRY is a prospective, multicenter, blinded outcome evaluation, observational trial, and aims to determine the functional outcomes and safety of endovascular treatment for AIS, due to vessel occlusion in anterior and posterior circulation, in routine clinical practice.

The primary endpoint is functional outcome, defined as a shift (improvement) in scores on the modified Rankin scale (mRS) at 90 days (±7 days).

Interventions

  • Device Endovascular treatment
    Endovascular treatment, such as mechanical thrombectomy with stent, aspiration catheter or stent assisted by intermediate aspiration catheter, as well as combination of mechanical thrombectomy with intra-arterial thrombolysis

Primary outcome measures

  • Functional outcome [Time frame: 90days]
Secondary outcome measures (6)
  • Dichotomized modified Rankin scale (mRS) [Time frame: 90days]
  • NIHSS at 24 hours [Time frame: 24 hours post-procedure]
  • NIHSS at 7 days [Time frame: 7 days post procedure]
  • Reperfusion outcome [Time frame: Immediately post-procedure]
  • Early successful revascularization rate [Time frame: During procedure]
  • Target vessel recanalization rate [Time frame: at 7 days post-procedure]

Eligibility criteria

Inclusion criteria

  • Acute ischemic stroke caused by anterior or posterior circulation vessel occlusion confirmed by computed tomography angiography (CTA) or magnetic resonance angiography (MRA) or digital subtraction angiography (DSA)
  • Undergo intravascular therapy (i.e. access to a cath lab and an arterial puncture)
  • The patient or his/her legal representative agreed to participate in the study and has signed the informed consent.

Exclusion criteria

1\) No exclusion criteria

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Jianimin Liu — Shanghai

Identifiers

NCT: NCT05864638 · OCIN-AIS-EVT REGISTRY

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗