Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Placebo Group, Whey Protein + Placebo, Omega 3 + Placebo, Omega 3 + Whey Protein.
- Who it may be relevant to
- Registry conditions: Sarcopenia. Basic parameters: 60 years — 85 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Brazil
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effects of Omega-3 and Whey Protein Supplementation on Lean Mass and Strength Gains in Older Adults Performing Resistance Exercise: A Randomized, Double-Blind and Placebo-Controlled Study
Overview
To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass and strength gains in older adults performing resistance exercise. Participants will be randomized into the 4 groups. The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin. The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin. The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil. The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein. All will perform the same exercise protocol for 12 weeks
Interventions
- Dietary supplement Placebo Group
The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin. - Dietary supplement Whey Protein + Placebo
The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil. - Dietary supplement Omega 3 + Placebo
The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin. - Dietary supplement Omega 3 + Whey Protein
The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein.
Primary outcome measures
- Changes in lean mass (kg) using ultrasound and electrical bioimpedance in postmenopausal women [Time frame: up to 12 weeks]
Secondary outcome measures (1)
- Changes in strength (kg) using dynamometer in postmenopausal women [Time frame: up to 12 weeks]
Eligibility criteria
Inclusion criteria
- Postmenopausal women (at least 1 year of menstrual interruption, self-reported);
- To be able to practice strength exercises;
- To be able to carry out supplementation;
- Do not present physical, orthopedic or cardiovascular complications that prevent the performance of physical exercises;
- No history of stroke or acute myocardial infarction;
- Not being a smoker and/or alcoholic;
- Do not perform hormone replacement therapy;
- Do not use anti-inflammatory drugs;
- To have normal kidney function;
- To submit a medical certificate of health that proves that the individual is able to perform exercises.
Exclusion criteria
- Do not provide the necessary information for the development of the study;
- Individuals with diseases previously diagnosed and undergoing treatment, such as type II diabetes mellitus, cancer, rheumatoid arthritis, high blood pressure, dyslipidemia, cardiovascular, and kidney and/or liver diseases.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
Brazil · 1 center
- Federal University of Uberlandia — Uberlândia
Identifiers
NCT: NCT05862779 · 5.728.049