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Enrolling by invitation NCT05832268

Pelvic Floor Function After Obstetric Injury to the Anal Sphincter

Observational Obstetric Anal Sphincter Injury Anal Incontinence Urinary Incontinence Sexual Dysfunction

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Obstetric Anal Sphincter Injury.
Who it may be relevant to
Registry conditions: Obstetric Anal Sphincter Injury, Anal Incontinence, Urinary Incontinence, Sexual Dysfunction. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Norway
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Pelvic Floor Future Study

Overview

The goal of this observational study is to learn more about the effect a pregnancy and delivery has on the function of the anal musculature.We will compare women who had a new delivery after suffering a severe tear in the anal musculature in their first pregnancy, with women who had two or more vaginal deliveries, but did not suffer such an injury. The main questions we want to answer is: * can the burden of a new pregnancy and delivery weaken the function of the repaired musculature in a way that might cause symptoms of anal incontinence later in life? * can a tear in the anal musculature increase the risk of developing urinary incontinence and long term sexual dysfunction? * should we recommend these women to have a caesarian section instead of a new vaginal delivery? Participants will be asked to complete an electronic questionnaire with information regarding their pregnancies, deliveries and potential symptoms from anal incontinence, urinary incontinence and sexual dysfunction. Researchers will compare these two groups to find out if a new vaginal delivery has a negative effect on the function of the anal musculature.

Interventions

  • Other Obstetric Anal Sphincter Injury
    We will investigate if a new vaginal delivery in those with a previous obstetric anal sphincter injury affects the function of anal musculature negatively

Primary outcome measures

  • The long-term impact of a new vaginal delivery on anal sphincter function in women with previous obstetric anal sphincter injury. [Time frame: 5- 20 years]
Secondary outcome measures (2)
  • Prevalence of urinary incontinence among women with previous OASI compared to women with similar parity without obstetric anal sphincter injury [Time frame: 5-20 years]
  • The risk of long- term dyspareunia and sexual dysfunction after previous obstetric anal sphincter injury compared to women with similar parity without obstetric anal sphincter injury. [Time frame: 5-20 years]

Eligibility criteria

Inclusion criteria

  • Sphincter group: Previous obstetric anal sphincter injury during vaginal childbirth in 2002-2018 and having a subsequent vaginal delivery without such injury
  • control group: Two or more vaginal deliveries without obstetric anal sphincter injury

Exclusion criteria

  • under 18 years
  • consent incompetency
  • Obstetric anal sphincter injury in subsequent pregnancies
  • caesarian section in subsequent pregnancy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Norway · 1 center
  • Oslo University Hospital — Oslo

Identifiers

NCT: NCT05832268 · 2019/654

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗