Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Prednisolone, Cerebrolysin.
- Who it may be relevant to
- Registry conditions: Bell Palsy. Basic parameters: 18 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy
Overview
Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies. Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy
Interventions
- Drug Prednisolone
prednisolone 60mg tablet once daily for 5 days then tapering dose - Drug Cerebrolysin
intramuscular Cerebrolysin 10 mg daily for 3 weeks
Primary outcome measures
- change in scores of the house Brackman grading system HB [Time frame: at baseline, after 1 week, after 3 week]
- changes in scores of the Sunnybrook grading system. [Time frame: at baseline, after 1 week, after 3 week]
Eligibility criteria
Inclusion criteria
- unilateral acute facial palsy of no identifiable cause
Exclusion criteria
- Recurrent facial Bell's palsy
- Pregnancy
- Diabetes
- Epilepsy
- Severe hypertension,
- Renal or hepatic disease,
- Gastric or duodenal ulcer
- presence of acute otitis media or ipsilateral chronic otitis
- Recent head injury,
- psychiatric disease
- If there is any contraindications for corticosteroids
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- October 6 university hospital — Giza
Identifiers
NCT: NCT05821075 · PRC-Ph-2211038