Longitudinal Study of Chronic Postsurgical Pain in Children and Adolescents
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Chronic Post Operative Pain. Basic parameters: 8 years — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Child and Parent Emotion-related Risk and Resilience Factors Associated With the Transition From Acute to Chronic Pain After Surgery: A Prospective Longitudinal Study
Overview
Chronic postsurgical pain is defined as pain that develops or intensifies following a surgical procedure. After major surgery, around 20% of children and adolescents develop chronic postsurgical pain, and, as part of it, negative consequences on their quality of life. Emotion-related factors such as the variability of emotions, how emotions are regulated, and how well someone is able to differentiate between different emotions have in part been studied in other types of chronic pain. To date, no study examined emotion-related factors in the development and maintenance of chronic postsurgical pain. This observational study includes five assessment time points, one before and four after major surgery, with the goal to identify emotion-related factors that increase or decrease the risk for the development of chronic postsurgical pain.
Primary outcome measures
- Chronic postsurgical pain [Time frame: 3 months]
- Pain trajectories [Time frame: 12 months]
- Emotion-related trajectories [Time frame: 12 months]
Secondary outcome measures (1)
- Physical activity [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Children and adolescents aged between 8 and 18 years
- Planned orthopedic surgery requiring in-patient care in one of the participating children's hospitals
- Able to read and understand German
Exclusion criteria
- Serious comorbid health condition (e.g., cancer, severe neurological impairment, chronic illness requiring daily medication)
- Prior major orthopedic surgery (e.g., prior spine surgery)
- Parent/caregiver and child not able to read and understand German
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Switzerland · 3 centers
- University Children's Hospital Basel — Basel
- University Children's Hospital Zurich — Zurich
- University Hospital Balgrist — Zurich
Publications
- Hochreuter J, Dreher T, Hasler CC, Canonica S, Locher C, Held U, Rabbitts J, Koechlin H. Longitudinal Resilience and Risk Factors in Pediatric Postoperative Pain (LORRIS): Protocol for a Prospective Longitudinal Swiss University Children's Hospitals-Based Study. BMJ Open. 2024 Mar 28;14(3):e080174. doi: 10.1136/bmjopen-2023-080174. PMID 38548365
Identifiers
NCT: NCT05816174 · LORRIS