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Recruiting NCT05808933

Magnetic Resonance Fingerprinting for Preoperative Evaluation of Lymphovascular Space Invasion in Early Stage Cervical Cancer

Observational Cervical Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Cervical Cancer. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The aim of this observational prospective study is to investigate the role of Magnetic Resonance Fingerprinting in preoperative assessment of early cervical cancer

Primary outcome measures

  • Association between T1-, T2- and ADC-maps and LVSI status [Time frame: 3 months]
Secondary outcome measures (2)
  • Correlation between T1-, T2- and ADC-maps and DFS and OS [Time frame: 3 years]
  • Correlation between Radiomics-based analysis and LVSI status and DFS and OS [Time frame: 3 years]

Eligibility criteria

Inclusion criteria

  • Patients with biopsy-proven cervical cancer FIGO stage IA-IIA undergoing surgery;
  • Women aged >18 years old;
  • Signed Informed Consent.

Exclusion criteria

  • Concurrent malignancies at other sites;
  • Previous history of neoplasm;
  • Refusal to sign written informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

Italy · 1 center
  • Fondazione Policlinico Universitaro "A. Gemelli" IRCCS — Roma

Identifiers

NCT: NCT05808933 · 4988

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗