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Recruiting NCT05802706

The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

— Observational Vascular Diseases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: No intervention..
Who it may be relevant to
Registry conditions: Vascular Diseases. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Ireland
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

Detailed description

The study is a non-randomised, controlled, cross-sectional study of diseased human carotid, femoral and abdominal aortic tissue.

Interventions

  • Other No intervention.
    No intervention.

Primary outcome measures

  • Calcification feature classification [Time frame: 10 years]
  • Biomarker Analysis [Time frame: 10 years]
Secondary outcome measures (1)
  • Cardiovascular Health Critical Mass [Time frame: 10 years]

Eligibility criteria

Inclusion criteria

  • Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
  • Able to provide informed consent.

Exclusion criteria

  • Patients that are unable to give informed consent.
  • Seriously ill/unconscious patients.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Ireland · 1 center
  • University Hospital Limerick — Limerick

Identifiers

NCT: NCT05802706 · DVS008

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗