Menu
Recruiting NCT05780957

Multi-Cancer Early Detection (MCED) of Firefighters

— Observational Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MCED.
Who it may be relevant to
Registry conditions: Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.

Interventions

  • Other MCED
    multi-cancer early detection (MCED) test

Primary outcome measures

  • Sensitivity, specificity, positive and negative predictive performance values (PPV and NPV) to detect cancer using Elypta's MCED test, as measured in plasma, in urine, and in plasma and urine combined [Time frame: Up to 7 years]
  • Sensitivity, specificity, positive and negative predictive performance values to detect cancer using Proteotype's MCED test, as measured in plasma. [Time frame: Up to 2030]

Eligibility criteria

Inclusion criteria

  • 18 years of age or older
  • Currently employed as a firefighter, full-time or part-time
  • Taking part in Vincere's First Responder Cancer Screening Program
  • Able to donate blood and urine sample
  • Able to provide informed consent to participate in the study

Exclusion criteria

  • Deemed medically unfit for sample donation
  • Personal history of cancer in the last 5 years (with the exception of non-melanoma skin cancer)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Vincere Cancer Center — Scottsdale

Identifiers

NCT: NCT05780957 · VCC-MCEDFF-001

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗