Menu
Recruiting NCT05779215

Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion

— Observational Acute Ischemic Stroke

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Visit at D90.
Who it may be relevant to
Registry conditions: Acute Ischemic Stroke. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Multicenter, Prospective, Real-world Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion

Overview

This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.

Detailed description

LOMEVO is a prospective, multicenter, real-world registry lasting for 10 years. A total of 50000 patients with large- or medium-vessel occlusion will be enrolled at approximately 30 centers around China.

Interventions

  • Other Visit at D90
    Visits at 90±7 days after stroke onset were conducted by trained and blinded investigators, with face-to-face, telephone call or Internet access.

Primary outcome measures

  • modified Rankin Scale (mRS) score [Time frame: 90±7 days]
Secondary outcome measures (11)
  • Excellent functional outcome [Time frame: 90±7 days]
  • Good functional outcome [Time frame: 90±7 days]
  • mRS 0-3 [Time frame: 90±7 days]
  • Change of National Institutes of Health Stroke Scale (NIHSS) [Time frame: 24 hours]
  • Change of National Institutes of Health Stroke Scale (NIHSS) [Time frame: 7 days]
  • Symptom-to-thrombolysis time (STT) [Time frame: 24 hours]
  • Door-to-Needle Time (DNT) [Time frame: 24 hours]
  • Door-to-Puncture Time (DPT) [Time frame: 24 hours]
  • Onset-to-recanalization time [Time frame: 24 hours]
  • Door-to-Recanalization Time (DRT) [Time frame: 24 hours]
  • Puncture-to-recanalization time [Time frame: 24 hours]

Eligibility criteria

Inclusion criteria

  • The clinical diagnosis is acute ischemic stroke with large- or medium- vessel occlusion (the criteria followed the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018)
  • Informed consent from the patient or surrogate

Exclusion criteria

  • No additional exclusion criteria

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Xuanwu Hospital, Capital Medical University — Beijing

Identifiers

NCT: NCT05779215 · XMEC-2023-002

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗