The Translational Initiative to Map Epigenetics in Aging (TIME-A)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Biological Aging. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The Translational Initiative to Map Epigenetics in Aging (TIME-A) study aims to advance our understanding of the connections between epigenetics, lifestyle, demographics, and health and aging.
Detailed description
TIME-A is a longitudinal research initiative. Anyone who has ever taken an Index test registered through Elysium Health is eligible to participate. Participation involves answering questions that will be administered via a survey format. Research participants' survey responses will be combined with their epigenetic Index data with the primary aim of identifying the contributions of 1) environmental and lifestyle factors, 2) general health, and 3) medical history, on biological age. Exploratory aims include the development of epigenetic signatures that are predictive of health status, and exploring the relationship between epigenetically-derived health phenotypes and biological age. These findings will lay the foundation for personalized health recommendations using Index (including, but not limited to: workout routines, diets, supplement regimens, medications, lifestyle changes).
Primary outcome measures
- Effect of environmental and lifestyle factors on biological age [Time frame: At baseline and throughout study (approximately every 6 months up to 120 months)]
- Effect of general health on biological age [Time frame: At baseline and throughout study (approximately every 6 months up to 120 months)]
- Effect of medical history on biological age [Time frame: At baseline and throughout study (approximately every 6 months up to 120 months)]
Eligibility criteria
Inclusion criteria
- All adults aged 18 and above
- Have registered at least one Index kit via the Elysium Health website
- Able and willing to provide digital consent to the Research Consent Form, and the TIME-A Research Subject Consent Form
Exclusion criteria
- Consent to participate not given
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT05760547 · TIME-A