Genetic Disorders of Obesity Program Database
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Obesity, Childhood, Genetic Disease. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study collects data on children with severe, early-onset obesity.
Detailed description
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children are asked to participate in a prospective, observational study. The investigators collect demographic information, body measurements, medical/family history, as well as other questionnaires. Additionally, genetic information, medical lab results, and responses to treatment options are collected. The goal of the study is to determine if the investigators can better understand which children would benefit from testing and further workup as well as to understand how obesity develops in these children and adolescents.
Primary outcome measures
- Prevalence of genetic causes of severe, early-onset obesity [Time frame: through study completion, an average of 10 years]
Secondary outcome measures (1)
- Change in BMI over time [Time frame: through participant completion, an average of 2 years]
Eligibility criteria
Inclusion criteria
- For individuals 2 years and older, BMI > 97 percentile
- For individuals < 2 years old, weight-to-length ratio > 95th percentile
Exclusion criteria
- No other exclusion criteria
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Baylor College of Medicine — Houston
Identifiers
NCT: NCT05747976 · H-44596